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* immunopath 8
 #134401  
  kashmala - 10/31/06 22:17
 
  A young male walks into an elevator full of people
who are coughing and sneezing, all of whom appear to
have colds or the flu. The influenza viral particles that he
inhales attach to respiratory epithelium, and viral transfor-
mation reduces the class I major histocompatibility com-
plex (MHC) molecules on these epithelial cells. Which of
the following cells then responds to destroy the infected
cells?
O (A) NK cell
(B) Neutrophil
(C) Macrophage
O (D) CD4 cell
O (E) Dendritic cell
 
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* Re:immunopath 8
#538448
  vl2ss - 10/31/06 22:19
 
  (A) NK cell
 
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* Re:immunopath 8
#538463
  zarra - 10/31/06 22:29
 
  a
 
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* Re:immunopath 8
#538492
  kashmala - 10/31/06 22:37
 
  yes A....weldone  
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* Re:immunopath 8
#538722
  kashmala - 11/01/06 02:38
 
  (A) NK cells have the ability to respond without
prior sensitization. They carry receptors for MHC class 1
molecules that inhibit their lytic function. When expression
of class I MHC molecules is reduced on the cell surface,
the inhibitory receptors on NK cells do not receive a nega-
tive signal. The cell is killed. NK cells are often the first
line of defense against viral infection. Neutrophils provide
a nonspecific immune response, primarily to bacterial in-
fections and not to intracellular viral infections. Macro-
phages can process antigen and can phagocytize necrotic
cells. CD4 cells are helper T cells that assist other cells,
such as NK cells, macrophages, and B cells, in the immune
response. Dendritic cells help in antigen presentation.
 
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