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| * nbme 3 genetics Q |
| | #531364 |
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Two inbred mouse strains,A and b,express different allele only at minor histocompatibility locus on Y chromosome.which of the following mice would accept a skin graft from a male (A*B) |
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| * Re:nbme 3 genetics Q |
| #2188515 |
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Two inbred mouse strains,A and b,express different allele only at minor histocompatibility locus on Y chromosome.which of the following mice would accept a skin graft from a male (A*B)F1 mouse with a strain A father and strain B mother?
a. (A*B)F1 female (A mother,B father)
b. (A*B)F1 female (A father,B father)
c. (A*B)F1 male (A mother,B father)
d. (A*B)F1 female (A father,B mother)
please explain ur answer. |
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| * Re:nbme 3 genetics Q |
| #2188578 |
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Donor: male (A*B)F1 mouse with a strain A father and strain B mother has Y from strain A.
a. (A*B)F1 female (A mother,B father) and b. (A*B)F1 female (A father,B father) are female (they have no Y) so they will recognize that allele on Y as non-self and will reject.
c. (A*B)F1 male (A mother,B father) has Y from strain B so will reject Y from strain A.
The only choice left is D which is from the same background composition as the donor and has Y from strain A like the donor.
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