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* DI vs SIADH vs Cerebral Salt Wasting Syndrome
 #503132  
  maverickdoctor - 04/30/10 11:51
 
  Can any one give the levels (low or high) of the following labs in each of the 3 conditions?

1. Urine output: DI vs SIADH vs CSW
2. Se. Na:..........
3. U. Na:..............
4. Se. Osm:...............
5. U. Osm:.....................
6. CVP-central venous pressure:.........
 
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* Re:DI vs SIADH vs Cerebral Salt Wasting Syndrome
#2095167
  maverickdoctor - 05/01/10 21:30
 
  ???????????????  
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* Re:DI vs SIADH vs Cerebral Salt Wasting Syndrome
#2095269
  pahology11 - 05/02/10 00:04
 
  anybody?

I start here: SIADH:

1. urine output:decreased
2.serum Na: decresaed
3.urine Na:>20mEq/L
4.urien osm: increased

we'll find you the lab values later.
 
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* Re:DI vs SIADH vs Cerebral Salt Wasting Syndrome
#2096544
  gaajo - 05/03/10 23:15
 
  CSW syndrome

1. Urine output:low
2. Se. Na low
3. U. Na:........... elevated
4. Se. Osm:........low
5. U. Osm:........ elevated
6. CVP-central venous pressure:.......hypovolemia

DI

1.Urine output...high(polyuria)
2.Se na ...high
3.Urine na...low
4.Se osm..high
5.U. osm.. low
6.CVS..............hypovelemia

SIADH
1.Urine output...low
2.Se na...low
3.Urine na...elevated
4.Se osm..low
5.U.osm...High
6.CVS...euvolemia or hypervolemia


correct me if iam wrong...
 
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* Re:DI vs SIADH vs Cerebral Salt Wasting Syndrome
#2096740
  pahology11 - 05/04/10 09:17
 
  gaajo,

at first glance I think you are right in most.

In CSW, urine output is high I believe.. thank you for posting.
 
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* Re:DI vs SIADH vs Cerebral Salt Wasting Syndrome
#2096958
  carlosaa - 05/04/10 12:57
 
  CSW mimics all of the laboratory findings in the SIADH. The only clue to the presence of CSW rather than SIADH is clinical evidence of extracellular volume depletion, such as hypotension and decreased skin turgor, and/or increased hematocrit, in a patient with a urine sodium concentration above 40 meq/L. Unlike SIADH, volume repletion in CSW leads to a dilute urine, due to removal of the hypovolemic stimulus to ADH release, and subsequent correction of the hyponatremia. This finding has not been convincingly demonstrated which could reflect concurrent SIADH due to the CNS disease.
In the setting of CNS disease, accurate distinction between CSW and SIADH is essential since the two disorders are managed differently, with possible adverse consequences if the incorrect therapeutic strategy is administered. In patients with a clinical picture compatible with CSW, we recommend initial therapy with isotonic saline to correct the volume depletion and possibly reverse the hyponatremia.
 
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* Re:DI vs SIADH vs Cerebral Salt Wasting Syndrome
#2096973
  pahology11 - 05/04/10 13:09
 
  great question and explanations . thank you.  
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* Re:DI vs SIADH vs Cerebral Salt Wasting Syndrome
#2097175
  maverickdoctor - 05/04/10 16:07
 
  CSW is increased Atrial natriuritic Peptide bcoz of low volume state. There is an inappropriately normal/low aldosterone and ADH levels despite high ANP.

DI vs SIADH vs CSW
1. Urine output:
2. Se. Na:..........
3. U. Na:..............
4. Se. Osm:...............
5. U. Osm:.....................
6. CVP-central venous pressure:.........
 
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* Re:DI vs SIADH vs Cerebral Salt Wasting Syndrome
#2097179
  maverickdoctor - 05/04/10 16:17
 
  DI vs SIADH vs CSW

1. U.O: Inc vs. Dec Vs. Inc
2. Se. Na: Inc Vs. Dec Vs. Dec
3. U. Na: Dec Vs. Inc Vs. Inc
4. Se. Osm:Inc Vs. Dec Vs. Dec/Normal
5. U. Osm: Dec Vs. Inc Vs. Dec/Normal
6. CVP: Dec/Normal Vs. Normal/ Inc Vs. Dec
 
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