* concepts of pathology only
		#564573
	messi121212 - 01/26/11 11:59
	please explain your concepts and learn it twice. in real exams, you will only be judge by your concepts. 1. A 40-year-old man has the recent onset of right-sided chest pain, difficulty breathing, and fever. On auscultation he has crackles, decreased respiratory sounds, and evidence of a right-sided pleural effusion. Which of the following best describes the expected type of inflammatory process involving the lung? A) Fibroblasts, collagen deposition, replacement of intrinsic tissue B) Macrophages, lymphocytes, increased concentrations of immunoglobulins C) Mast cells, histamine, smooth muscle contraction D) Neutrophils, increased vascular permeability, edema E) Vascular budding, fibroblasts, edema, proteoglycans 5. A 57-year-old man receives a sintered titanium oxide implant during total hip arthroplasty following traumatic injury. During the first 6 weeks following surgery, bone ingrowth anneals to the bone-metal interface in both the femur and acetabulum, thus securing the prosthesis in position. Type I collagen secretion in the first stage of matrix formation is mediated by which of the following cell types? A) Chondroblasts B) Chondrocytes C) Endothelial cells D) Macrophages E) Osteoblasts F) Osteoclasts G) Osteocytes 23. explain a blood vessel, what is the principal site of nitric oxide action in producing vasodilation? CELL INJURY 39. In reversible hypoxic cell injury, cellular swelling results from intracellular accumulation of A) cholesterol B) glycogen C) phospholipid D) potassium E) sodium CELL INJURY 22. An 18-year-old man attempts suicide by taking 15 g of acetaminophen. Four hours after the overdose, high levels of acetaminophen are found in the plasma. The most appropriate therapy is A) hemodialysis B) oral administration of aspirin C) oral administration of N-acetylcysteine D) respiratory support and watchful waiting E) urinary alkalinization and forced diuresis CELL INJURY 36. An adult's hemoglobin is 98% saturated with oxygen, but arterial oxygen content is decreased. The most likely cause of this condition is A) anemia B) an arteriovenous shunt C) hemoglobinopathy D) high-altitude hypoxia E) pulmonary diffusion defect MUSCULOSKELETAL 9. A 61-year-old woman has a 10-year history of progressive pain in the hips, knees, and hands. She has symmetric swelling and formation of nodules in the distal interphalangeal joints of her hands and pain on movement of both knees. There is no increased warmth or tenderness. The most likely cause of her joint pain is A) gout B) Lyme disease C) osteoarthritis D) pseudogout E) rheumatoid arthritis COAGULATION 10. A 3-year-old boy with cystic fibrosis is evaluated for the acute onset of an uncontrollable nosebleed. There is no family history of a bleeding disorder. A few large bruises are seen on the legs; no other abnormalities are noted. Prothrombin and partial thromboplastin times are prolonged. The patient's abnormalities are likely to improve with treatment using a cofactor for which process? A) Carboxylation of prothrombin B) Conversion of homocysteine to methionine C) Farnesylation of ras D) Hydroxylation of procollagen E) Phosphorylation of pyruvate dehydrogenase
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