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* NBME 4 block 4 Q 1 to 50
 #583376  
  maryam2009 - 05/01/11 22:24
 
  Welcome....,Please choose and answer the Qs in order. We are always looking for more volunteers. ... Any help would be appreciated .Thank you.  
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* Re:NBME 4 block 4 Q 1 to 50
#2387689
  maryam2009 - 05/01/11 22:29
 
  1.AA

tRNA has a 3' terminal site for amino acid attachment. This covalent linkage is catalyzed by an aminoacyl tRNA synthetase. It also contains a three base region called the anticodon that can base pair to the corresponding three base codon region on mRNA
 
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* Re:NBME 4 block 4 Q 1 to 50
#2387693
  maryam2009 - 05/01/11 22:40
 
  2.DD

Hepatic gluconeogenes is dependent on 2 enzymes:
1.Pyrovate caroxylase......it helps the pyrovate to become Oxaloacetate..vit B7 is essensial

2.PEPK...Phosphenolpyruvate carboxykinase...it helps oxaloacetate to become PEP(phosphenolpyrovate)


 
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* Re:NBME 4 block 4 Q 1 to 50
#2387701
  sash11 - 05/01/11 22:57
 
  3.C
PKA is also known as cAMP-dependent protein kinase. Protein kinase A has several functions in the cell, including regulation of glycogen, sugar, and lipid metabolism.
Each PKA is a holoenzyme that consists of two regulatory and two catalytic subunits. Under low levels of cAMP, the holoenzyme remains intact and is catalytically inactive. When the concentration of cAMP rises (e.g., activation of adenylate cyclases by G protein-coupled receptors coupled to Gs, inhibition of phosphodiesterases that degrade cAMP), cAMP binds to the two binding sites on the regulatory subunits, which leads to the release of the catalytic subunits.
 
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* Re:NBME 4 block 4 Q 1 to 50
#2387704
  sash11 - 05/01/11 23:06
 
  4.A
A T-tubule is a deep invagination of the sarcolemma, which is the plasma membrane, only found in skeletal and cardiac muscle cells. These invaginations allow depolarization of the membrane to quickly penetrate to the interior of the cell.
 
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* Re:NBME 4 block 4 Q 1 to 50
#2387888
  doc_study - 05/02/11 10:39
 
  4. A

DMD is X-linked recessive . in x-linked inheritance male is either normal or diseased BUT "NOT CARRIER".

Posted by sarim

Also for information,

http://www.uic.edu/classes/bms/bms655/lesson7.html
 
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* Re:NBME 4 block 4 Q 1 to 50
#2387894
  doc_study - 05/02/11 10:43
 
  *************correction*********

Its Q no. 5.

Answer is A.

DMD is X-linked recessive . in x-linked inheritance male is either normal or diseased BUT "NOT CARRIER".

Posted by sarim

Also for additional information,

http://www.uic.edu/classes/bms/bms655/lesson7.html
 
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* Re:NBME 4 block 4 Q 1 to 50
#2387911
  doc_study - 05/02/11 11:13
 
  6. B

Chemotactic substanceS for neutrophils are

IL-8, C5a, LTB4, Fibrinopeptides (fibrin clot degradation) & Formyl methionine peptides (bacterial products)
 
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* Re:NBME 4 block 4 Q 1 to 50
#2388074
  maryam2009 - 05/02/11 17:43
 
  7.AA
receptors with Tyrosine kinase motifs have a transcriptional
activity...
http://www.youtube.com/watch?v=3nODx3cT1RU&feature=related
 
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* Re:NBME 4 block 4 Q 1 to 50
#2388083
  maryam2009 - 05/02/11 18:01
 
  8.BB

Alcoholics Anonymous (AA) is an international mutual aid movement declaring its "primary purpose is to stay sober and help other alcoholics achieve sobriety.

An Alcoholics Anonymous (AA) meeting is a support group for alcoholics who are breaking their addiction. Members will often meet to share experiences on problems with their lives, recent developments, and how long they have been sober.

 
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* Re:NBME 4 block 4 Q 1 to 50
#2388124
  maryam2009 - 05/02/11 19:43
 
  10.FF

The partial agonist X acts on the same receptor system that full agonist (NOREPINEPHRINE),but has a LOWER MAXIMAL EFFICACY regardlees of the dose.A partial agonist may be more potent ..as in the figure ,less potent or equally potrent.
potency is an independent factor
 
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