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* NBME 7 block 3 q 1 to 50
 #585725  
  maryam2009 - 05/13/11 11:25
 
  Welcome....,Please choose and answer the Qs in order. We are always looking for more volunteers. ... Any help would be appreciated .Thank you.  
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* Re:NBME 7 block 3 q 1 to 50
#2394543
  maryam2009 - 05/13/11 11:58
 
  1.AA

If there is no other bias in the study, statistical significance guarantees that there is a 95 percent chance that the study’s result reflects what is happening in the population at large.

 
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* Re:NBME 7 block 3 q 1 to 50
#2394551
  maryam2009 - 05/13/11 12:12
 
  2.CC

Opioid receptors are a group of G protein-coupled receptors with opioids as ligands.
Morphine is shown to bind to mu receptors.
 
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* Re:NBME 7 block 3 q 1 to 50
#2394556
  maryam2009 - 05/13/11 12:20
 
  3.DD

The jugular foramen may be subdivided into three compartments, each with their own contents.

The anterior compartment transmits the inferior petrosal sinus.
The intermediate transmits the glossopharyngeal, vagus, and accessory nerves (aka cranial nerves number IX, X, and XI respectively).
The posterior transmits the sigmoid sinus (becoming the internal jugular vein) and some meningeal branches from the occipital and ascending pharyngeal arteries.

In this case the Sternocleidomastoid m. and Trapezoid are inervated by Accessory n.....XI
 
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* Re:NBME 7 block 3 q 1 to 50
#2394560
  dna23 - 05/13/11 12:29
 
  2 --AA Zafirlukast and montelukast are antagonist at LTD4 receptors with slow onset of activity used prophylactically for different form of asthma for example the exercise or drugs like ASA
Ipatropium cause bronchodilation in acute asthma----used in COPD and safer than B agonist
in patients wit CV disease
Theophyline ----bronchodilates via inhiubition of Phosphodiesterase PDE ----increased cAMP
and also by antagonist of adenosine(bronchoconstrictor)
The final step of this 3 groups of medicine is work over the bronchospasm
 
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* Re:NBME 7 block 3 q 1 to 50
#2394562
  maryam2009 - 05/13/11 12:32
 
  4.EE

The antimicrobial resistance to all mentioned antibiotics ....Beta-lactam antibiotics(Penicillin and its generation) is caused by production of extended-spectrum beta lactamase
 
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* Re:NBME 7 block 3 q 1 to 50
#2394564
  dna23 - 05/13/11 12:35
 
  Sorry, the explanation was to Q-2 and block 1  
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* Re:NBME 7 block 3 q 1 to 50
#2394581
  maryam2009 - 05/13/11 13:04
 
  5.CC

X-linked recessive inheritance is a mode of inheritance in which a mutation in a gene on the X chromosome causes the phenotype to be expressed
(1) in males (who are necessarily hemizygous for the gene mutation because they have only one X chromosome) and
(2) in females who are homozygous for the gene mutation (i.e., they have a copy of the gene mutation on each of their two X chromosomes)....so it is 2:1

 
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* Re:NBME 7 block 3 q 1 to 50
#2394584
  dna23 - 05/13/11 13:08
 
  5- AA this Q don't have all the information requiered to give the answer, don't says nothing about her husband; but CARRIER female has half of the son affected and half of the daughters carrier then 50/50 (1.1)  
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* Re:NBME 7 block 3 q 1 to 50
#2394596
  maryam2009 - 05/13/11 13:23
 
  The Q is about the expected ratio of carrier mother viable female to male children for X-linked recessive disease...the female child must get another affected X from daddy..to become sick so she needs to receive two genes,but male child just needs one X that it comes from her carrier mother to get the disease...so the ratio of getting affected X between female and male children is 2:1  
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* Re:NBME 7 block 3 q 1 to 50
#2394602
  dna23 - 05/13/11 13:26
 
  It's true your right, Thanks.  
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