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* NBME 12 block 4 questions
 #626140  
  mmusmle - 10/28/11 16:53
 
  8. A 4-year-old boy has a 2-month history of easy bruisability, petechial hemorrhages, and bleeding gums. He has hepatosplenomegaly and pancytopenia. Examination of
bone marrow shows marrOW infiltration with a homogeneous population of small blast-like cells with large nuclei and scant cytoplasm. These infiltrating cells have the
following immunophenotype: CD22+, CD19+, cytoplasmic Ig~+, cytoplasmic IgK-, cytoplasmic IgA-, surface Ig-, CD3-. The patient most likely has an acute leukemia
originating from which of the following cells?
o A) Immature myelomonocytes
o B) Mature B lymphocytes
o C) Mature monocytes
o D) Mature T lymphocytes
o E) Pre-B lymphocytes
o F) Pre-T lymphocytes

Ans E because it is CD3-and CD 19+ also T-cell should be CD3+
I have a doubt here Goljan on page 235 of rapid review says that T-cell ALL arises from T cells whereas UW says T-cell All arises from Pre T lymphocytes if anybody what is correct pl explain


9. A 32-year-old woman undergoes a laparoscopic cholecystectomy after ultrasonography showed a thickened gallbladder wall and gallstones. The surgeon will be unable to
inspect directly which of the following organs during this procedure?
o A) Ileum
o B) Jejunum
o C) Pancreas
o D) Stomach
o E) Transverse colon

Ans Pancreas being retroperitoneal


18. A 6-hour-old female newbom has a harsh systolic murmur at the left upper stemal border. Findings on physical examination are otherwise unremarkable. Three hours
later, the murmur has a diastolic component Twelve hours later, there is no murmur, and ultrasonography discloses no cardiac abnormalities. Which ofthe following is the
most likely cause of the murmur?
o A) Mitral regurgitation
o B) Patent ductus arteriosus
o C) Persistent truncus arteriosus
o D) Transient tricuspid insufficiency
o E) Ventricular septal defect with right-to-left shunt

Ans is PDA If anyone knows pl explain


40. Assume that any single laboratory test in a three-test battery obtained from healthy volunteers has a 5% chance of falling outside of the "normal" range. Which of the
following is the closest probability that a healthy person will have normal results for all three tests?
o A)5%
o 8)40%
o C)85%
o D)95%

Ans is C why ?/ Pl explain

 
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* Re:NBME 12 block 4 questions
#2512574
  mmusmle - 10/28/11 17:41
 
  Any one  
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* Re:NBME 12 block 4 questions
#2512591
  mmusmle - 10/28/11 18:40
 
  For q 8 it is pre T cell

For q 18 it is PDA since since it has systolic as well as diastolic component and would have closed by Indomethacin Rx so no murmur and no defect


The only question 40 I could find out
Any kind soul please help

Thanks
 
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* Re:NBME 12 block 4 questions
#2513410
  nonyelum - 10/30/11 00:21
 
  Hi mmusmle,pls could u send me d link of NBME 12 to my inbox,nonyell@yahoo.com. Tnk u  
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* Re:NBME 12 block 4 questions
#2611782
  vera16 - 03/12/12 12:18
 
  #18. PDA

This is my explanation...
This infant has PDA which normally disappear shortly after birth or it must be disappeared by 1yr.
 
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* Re:NBME 12 block 4 questions
#2611785
  vera16 - 03/12/12 12:19
 
  Someone please help to explain #40...Thanks!

40. Assume that any single laboratory test in a three-test battery obtained from healthy volunteers has a 5% chance of falling outside of the "normal" range. Which of the
following is the closest probability that a healthy person will have normal results for all three tests?
o A)5%
o 8)40%
o C)85%
o D)95%

Ans is C why ?/ Pl explain
 
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* Re:NBME 12 block 4 questions
#2611957
  mdhouse1282 - 03/12/12 13:36
 
  q 40
.95*.95*.95=.85
 
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* Re:NBME 12 block 4 questions
#2612172
  timmalik - 03/12/12 15:07
 
  8. pre B lymphocyte.CD19 and CD22+
9.C
18.B
40 85%
 
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* Re:NBME 12 block 4 questions
#2614228
  vera16 - 03/13/12 16:46
 
  I figure out #40...yayyy! =)

in each test, there's 0.5 % chance of not having a normal result.....and there are 3 tests

0.5x 3=0.15...(not having a normal result of all 3 tests)

and we are looking for the one that is normal

so 1.00- 0.15=0.85 or 85% (normal result)
 
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* Re:NBME 12 block 4 questions
#2614243
  vera16 - 03/13/12 16:56
 
  I figure out #40...yayyy! =)

in each test, there's 0.5 % chance of not having a normal result.....and there are 3 tests

0.5x 3=0.15...(not having a normal result of all 3 tests)

and we are looking for the one that is normal

so 1.00- 0.15=0.85 or 85% (normal result)
 
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* Re:NBME 12 block 4 questions
#2614246
  vera16 - 03/13/12 16:57
 
  I figure out #40...yayyy! =)

in each test, there's 0.5 % chance of not having a normal result.....and there are 3 tests

0.5x 3=0.15...(not having a normal result of all 3 tests)

and we are looking for the one that is normal

so 1.00- 0.15=0.85 or 85% (normal result)
 
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