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* to maryam plz help
 #662468  
  step1fire - 03/14/12 12:24
 
  A 35-year-old woman is brought to the emergency department after she sustains a fracture of the neck of the fibula of her right leg. She was struck by a car while crossing the street. Which of the following findings is most likely on examination of the affected leg?
Pain Over ---------Pain Over
Proximal Fibula -Distal Fibula- Dorsiflexion- Plantar Flexion -Achilles Reflex
A Absent ------------absent 4/5 1/5 1+

B Absent ------------present 015 4/5 1 +

C Present ------------absent 1/5 4/5 2+

D Present -----------absent 5/5 0/5 absent


E Present ------------present 4/5 4/5 2+


IS IT B?

A study is conducted to assess whether there is a relationship between daily fish oil intake and renal disease progression in patients with IgA nephropathy. A total of 250 patients with biopsy-proven IgA nephropathy are enrolled: 125 patients are assigned to receive 4g of fish oil concentrate daily and 125 patients are assigned to receive a placebo. The treating physicians are blinded to which patients are receiving fish oil and which are receiving placebo. Renal function in these patients is assessed on a semiannual basis for the next 10 years, and the number of patients who develop end-stage renal disease in each group is noted. Which of the following is the strongest rationale for randomization?
(a) ↓ the risk of bias (b) ↓ the risk of a type II error (c) ↓ the sample size required to obtain significant results
(d) ensures that all patients have valid disease (e) ↑ the power of the study


i marked e its wrong plz tel wats the right answer


Metaphyseal dysplasia due to single gene disorder caused by mutation in PTH receptor gene. Phenotype is "similar to that of acquired hyperparathyroidism." Mechanism?

Haploinsufficiency -
Dominant Negative
Gain of function
Pleiotropy
Anticipation

I GUESS ITS GAIN OF FUNCN...PLZ EXPLAIN


PLZ HELP ME UNDERSTAND THESE QUSNS THANKS
 
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* Re:to maryam plz help
#2615486
  maryam2009 - 03/14/12 12:31
 
  please lable the NBME#  
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* Re:to maryam plz help
#2616874
  maryam2009 - 03/15/12 07:27
 
  #13 ??
 
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* Re:to maryam plz help
#2617153
  sarim - 03/15/12 12:06
 
  C- Present ------------absent 1/5 4/5 2+

(a)- ↓ the risk of bias


Gain of function


 
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* Re:to maryam plz help
#2617159
  maryam2009 - 03/15/12 12:11
 
  Since I do not want to be exposed by the new NBME,I avoided reading the Q

Thank you Sarim :)
 
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