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| * Re:NBME 17 - Help Please - Test in 4 days! |
| #3203436 |
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This is how I thought about it.
The question tells you that the child with question mark doesn't have the disease then what alleles would he most likely have. We know that APKD is a autosomal dominant disease so we look back at the father and we know that the 1 allele is the allele that expresses the disease because both his father and brother share at least one 1 allele. so if the son with the question mark doesnt have the disease at all, then he must have inherited the 3 from the father and 2 from the mother because she is 2,2.
dont be confused, the question is asking what alleles is the son a carrier for not that he must be a carrier of the disease because you cant be a carrier of a AD disease and not express it.
hope this helps! |
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