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* Re:Q@Q time
 #846448  
  vcampech2 - 12/19/17 19:53
 
  Ms. Parker, a 46-year-old bank executive, is referred by her dentist. She had complaints of swollen and bleeding gums for 6 weeks. She appears pale and complains of feeling weak. She smokes half a pack of cigarettes and drinks socially. Her family history is not significant. Her vitals are stable and she is afebrile. CBC reveals:

WBC 44,100mm3
Hemoglobin 10.0
Hematocrit 32%,
Platelets 16,000mm3


The leukocyte distribution is as follows

Blast forms 79%
Promonocytes 12%
Monocytes 8%
Lymphocytes 1%


Cytochemical tests are ordered and they are as under:

Sudan Black Slightly positive
Alpha-naphthyl esterase Positive
PAS reaction Negative


What is the most probable diagnosis?


A. Acute myeloblastic leukemia with maturation
B. Acute promyelocytic leukemia
C. Acute lymphoblastic leukemia
D. Acute erythro leukemia
E. Acute monocytic leukemia
 
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* Re:Re:Q@Q time
#3355692
  shinenrise - 12/20/17 00:00
 
  E. gum hyperplasia (blasts infiltrate gums)  
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* Re:Re:Q@Q time
#3355727
  jomerugu - 12/20/17 12:53
 
  APML  
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* Re:Re:Q@Q time
#3355734
  yohana17 - 12/20/17 14:10
 
  B. Acute promyelocytic leukemia  
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* Re:Re:Q@Q time
#3356339
  vcruz - 12/30/17 18:47
 
  E) Bleeding gums and swollen is characteristic(but not exclusive) and 12% monocites.
But is curious because AML is usually PAS positive
 
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