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* Mechanism for metronidazole and daptomycin
 #846497  
  2pac - 12/21/17 19:01
 
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* Re:Mechanism for metronidazole and daptomycin
#3356205
  visceralpleura - 12/28/17 14:51
 
  Daptomycin

Daptomycin inserts into the cell membrane, where it then aggregates. The aggregation of daptomycin creates holes that leak ions. This causes rapid depolarization, resulting in a loss of membrane potential leading to inhibition of protein, DNA and RNA synthesis, which results in bacterial cell death.
 
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