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* blood transfusion reactions
 #852123  
  adair - 06/13/18 02:58
 
  if there is ABO missmatch patient shows hemolysis and this happens whitin minutes-hours cause we all have anti ABO s in our body since childhood and they r ready to fight against non similiar ABO antigens so this is an example of hyperacute graft rejection and a type2 hypersensitivity,,i hope i got it right

my question is what is the story about Rh missmatch? since we do n ot have anti Rh in our body unless we have been exposed before sometime during life -pregnancy,abortion or previous blood transfusion--- so now if person for first time receives a blood with missmatched Rh will he show hemolysis aswell? or he just becomes sensetized and makes memory cells which can react in later transfusion in a hyperacute manner?

thanks in advance
 
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* Re:blood transfusion reactions
#3368094
  zalak148 - 06/13/18 05:40
 
  the person receiving Rh incompatible blood transfusion for the first time will not show any symptoms or may show milder symptoms but if he is exposed to Rh incompatible blood for the second time his body will mount an immune response due to preformed antibodies (type 2 hypersensitivity) .but again ABo incompatibility symptoms are much more severe. hope this helps :)  
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