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* Test your knowledge (provide explanation too pls)
 #862327  
  jd2020 - 05/16/20 07:44
 
  A 44-year-old woman comes to the office due to a rash. She has experienced recurring "red spots" on her legs for 2–3 years. These appear sporadically, last a few weeks to a few months, and disappear spontaneously. The rash is not pruritic. When it occurs, the patient also experiences generalized fatigue and arthralgias involving her hips and knees. She rarely has right lower quadrant pain with the rash. Review of systems is otherwise normal.
Medical history is unremarkable. The patient has no known drug allergies. Her only medication is an oral contraceptive, which she has taken for several years. She does not use tobacco, alcohol, or illicit drugs. She is single and works in an office.
On examination, the patient appears healthy. Blood pressure is 136/86 mm Hg, pulse is 72/min, and respirations are 14/min. BMI is 24 kg/m2. Physical examination is normal except for the skin. A total of 10–12 palpable red lesions, measuring 1×0.5 cm, are scattered over both lower extremities distal to the mid-calf. The lesions are nontender and do not blanch with pressure.
Laboratory results are as follows:
Blood
Hematocrit 38%
Platelets 240,000/mm3
Leukocytes 8,000/mm3
Creatinine 1.4 mg/dL

Urinalysis
Specific gravity 1.020
Protein 2+
Blood trace
Glucose negative
Ketones negative
Leukocyte esterase negative
Nitrites negative
White blood cells 1–2/hpf
Red blood cells 10–20/hpf
Casts occasional red blood cell casts


Which of the following would most likely be found in this patient?
Answer Choices
A) Anti–double-stranded DNA antibodies
B) Anti–hepatitis C virus antibodies
C) Anti-Ro antibodies
D) Capillary IgA deposits on skin biopsy
E) Focal glomerular sclerosis on renal biopsy


 
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* Re:Test your knowledge (provide explanation too pl
#3388795
  cocele - 06/03/20 04:23
 
  HSP - D  
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* Re:Test your knowledge (provide explanation too pl
#3388812
  ngty1991 - 06/04/20 13:26
 
  D- first you have to consider what condition it is. Because its dermatological and looking at the answer choices, its either SLE or HSP. SLE presents with much mroe severe and variability of symptoms so answer is D.

The other answer choices do not have the specific skin presentation like this patient.
 
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* Re:Test your knowledge (provide explanation too pl
#3389041
  longway2go - 06/20/20 20:34
 
  Hi, So is the diagnosis Henoch Schonlein Purpura?
 
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