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nbme 2/32 - diabolic
#1
32. A 10-year-old boy is brought to the physician
because of
weakness and decreased appetite for 3 months. He
weighs 30 kg (66 lb) and is
142 cm (56 in) tall; he has had a 2.3-kg (5-lb) weight
loss since his
last examination 6 months ago. He appears thin. Deep
tendon reflexes
are brisk. Chvostek's sign is positive. His serum
calcium level is 6.5
mg/dL, and serum intact parathyroid hormone level is
190 pg/mL
(N=9“65). In addition to calcium supplementation,
which of the following is
the most appropriate next step in management?
A
) Oral phosphate supplementation
B
) Oral vitamin D supplementation
C
) Intranasal calcitonin therapy
D
) Parenteral bisphosphate therapy
E
) Parenteral parathyroid hormone therapy

???

y not calcitonin
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#2
is it.....B ??
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#3
nop, calcitonin can decrease ca level, now ca is already low.

The picture is...weakness and decreased appetite for 3 months...that cause vit D def...low ca absorption from GI.. low serum ca...activate parathyroid....so PTH increase.

So, main defect is low vit D, give B, oral vit D.
This is Secondary hyperparathyroidism...Hope you got it,
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#4
nop, calcitonin can decrease ca level, now ca is already low.

The picture is...weakness and decreased appetite for 3 months...that cause vit D def...low ca absorption from GI.. low serum ca...activate parathyroid....so PTH increase.

So, main defect is low vit D, give B, oral vit D.
This is Secondary hyperparathyroidism...Hope you got it,
Reply
#5
1.his weight and height is less for his age ..has growth retartdation ,any chronic process causing this.
2.calcium is definitely low ,PTH high =secondary hyperparathyroidism
to reduce bone resorption ,BISPHOSPHONATE IS NOT A BAD OPTION ,IN addition to Ca supplementation ..
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