11-27-2007, 08:20 AM
A 62-year-old man with a history of longstanding diabetes mellitus and hypercholesterolemia
presents to the emergency department with substernal chest pain for 90 minutes. Pain is
grade 9/10 radiating to the left arm and not relieved by nitroglycerine. His 12-lead
electrocardiogram (ECG) on presentation shows ST-segment elevation in leads V1 through
V5. Physical examination is within normal limits, with lungs clear to auscultation, no edema,
and normal rate and rhythm of heart rate. Temperature is 36.8 C (98.2 F), blood pressure is
130/87 mm Hg, pulse is 90/min, and respirations are 18/min. Which of the following
medications has been shown to be the most effective pharmacotherapy in reducing mortality in
this setting?
A. Aspirin
B. ACE inhibitor
C. Beta-blocker
D. Calcium channel blockers
E. Morphine
presents to the emergency department with substernal chest pain for 90 minutes. Pain is
grade 9/10 radiating to the left arm and not relieved by nitroglycerine. His 12-lead
electrocardiogram (ECG) on presentation shows ST-segment elevation in leads V1 through
V5. Physical examination is within normal limits, with lungs clear to auscultation, no edema,
and normal rate and rhythm of heart rate. Temperature is 36.8 C (98.2 F), blood pressure is
130/87 mm Hg, pulse is 90/min, and respirations are 18/min. Which of the following
medications has been shown to be the most effective pharmacotherapy in reducing mortality in
this setting?
A. Aspirin
B. ACE inhibitor
C. Beta-blocker
D. Calcium channel blockers
E. Morphine