02-28-2008, 08:00 AM
Of the following, which is unlikely to be associated with receptors bound to plasma membranes, their interaction with ligands, and the biologic response to this interaction?
A.
Structurally, these receptors have hydrophobic amino acid domains, which are in contact with the membrane, and hydrophilic regions, which extend into the extracellular fluid and the cytoplasm
B.
Chemical interactions of ligands with these receptors may involve the formation of many types of bonds, including ionic, hydrogen, van der Waals', and covalent
C.
Ligand-receptor interactions are often stereospecific (i.e., one stereoisomer is usually more potent than the other)
D.
In some cases, a ligand that acts as an agonist at membrane-bound receptors increases the activity of an intracellular second messenger
E.
Activation of membrane-bound receptors and subsequent intracellular events elicit a biologic response through the transcription of DNA
A.
Structurally, these receptors have hydrophobic amino acid domains, which are in contact with the membrane, and hydrophilic regions, which extend into the extracellular fluid and the cytoplasm
B.
Chemical interactions of ligands with these receptors may involve the formation of many types of bonds, including ionic, hydrogen, van der Waals', and covalent
C.
Ligand-receptor interactions are often stereospecific (i.e., one stereoisomer is usually more potent than the other)
D.
In some cases, a ligand that acts as an agonist at membrane-bound receptors increases the activity of an intracellular second messenger
E.
Activation of membrane-bound receptors and subsequent intracellular events elicit a biologic response through the transcription of DNA