04-29-2008, 03:09 PM
A 65-year-old woman comes to the physician because of a two-month history of fatigue and weight gain. She has rheumatoid arthritis and hypertension. She takes hydrochlorothiazide and naproxen. She does not use tobacco, alcohol, or drugs. Her blood pressure is 120/70 mm Hg, pulse is 80/min, and respirations are 14/min. Physical examination shows generalized edema; liver is palpated 2 cm below the costal margin. Urinalysis shows 4+ proteinuria. Ultrasound of the kidneys shows slight enlargement. Renal biopsy was performed. Which of the following is the most likely finding on renal specimen analysis?
A)
Crescent formation on light microscopy
B)
Deposits revealed under polarized light
C)
Linear immunoglobulin deposits revealed on immunofluorescence microscopy
D)
Granular immunoglobulin deposits revealed on immunofluorescence microscopy
E)
Normal light microscopy findings
A)
Crescent formation on light microscopy
B)
Deposits revealed under polarized light
C)
Linear immunoglobulin deposits revealed on immunofluorescence microscopy
D)
Granular immunoglobulin deposits revealed on immunofluorescence microscopy
E)
Normal light microscopy findings