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One method of getting drugs past the blood brain barrier is to inject a solution with a high osmolarity first and then follow with the drug injection. Why does this work?

Thank you very much

sigh.

Nobody knows!!!!!!!!!!

what i know something related to BBB that, there are some places in brain, which have no bbb present such as area postrema...

This question is so simple.
If you do not know the answer, it's hard for you to obtain high scores in Step 1.

THE HYPEROSMOLAR SOLN PROBABLY forces out water from behind the BBB, and partially disrupts it/makes it more permeable, during which time, any other substances will have a free-er access to the inside...