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The proliferation of cytotoxic T cells is markedy impaired by HIV virus. The defect has been traced to the expression of a viral-encoded enzyme that inactivates a host-cell nuclear protein required for DNA replication. Which protein is a potential substrate for the viral enzyme?

A. TATA-box binding protein (TBP)
B. Cap binding protein (CBP)
C. Catabolite activator protein (CAP)
D. Acyl-carrier protein (ACP)
E. Single-strand binding protein (SSBP)

if it is replication it's going to be E. single stranded binding protein, please correct me if i am wrong.
thank you

i think so u r right

You both got it right. Actually they are testing if you totally understand replication event. Helicase, SS DNA-binding protein, primase, ligase DNA topoisomerase etc are associated with DNA replication.

TBP and CBP are something about transcription. CAP regulates the expression of lactose operons. ACP is involved in fatty acid synthesis. That leaves only E. Using exclusion will bring you to the right answer.