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A 2-year-old boy has a unilateral cleft lip and cleft palate. He has no family history of birth defects. His parents are not related. Which of the following genetic mechanism is most likely to have caused these congenital abnormalities?

A- Autosomal dominat inheritance

B- Autosomal recessive inheritance

C- Chromosome aneuploidy

D- Chromosome deletion

E- Mitochondrial DNA mutation

F- Multifactorial Inheritance

G- X-Linked Recessive

F.

yup agree..

why f. this looks like pataus syndrome. mitochandrial inharitance are from mother. but there is no family history. i think it's chromasal abnormality

Waheed, the answer is not mitochondrial inheritance, but multifactorial Inheritance. Cleft lip is a typical example of multifactorial inheritance.

F is right answer.
Saton somewhere you wrote about Q site USMLE 123 ,where can I find it?

dear saton,
if u hv nbme 2 q's as a folder, can u email it to me plz on sonalaamod
thanks

Shamsnab try this link
http://www.studentconsult.com/usmle/


Diligent: I dont have a folder of the questions, I write it while I was doing the test. I will post every Q that I have written in this forum.