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Full Version: nbme 15 q? - alekyamanasa03
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difference in pathway of ikb of nfkb from il 1 to IL 6?

a attaches to cytokine receptor
b facilitates cleavage of nfkb
c phosphorylates nfkb
d releases nfkb after phosphoryltaion
e translocation to nucleus after undergoing phosphorylation
answer?
ddd
ikk phosphorylates ikb-nfkb complex n releases nfkb n this nfkb translocates to the nucleus to bind to response elements. ikb is inhibitory to nfkb. nkfb is present in the cytoplasm.
so first option D will take place then option E will take place.
but it seems there is difference in the pathway for IL 1 to IL 6,
wHAT IS IT?