+- USMLE Forum - Largest USMLE Community (https://www.usmleforum.com)
+-- Forum: USMLE Forum (https://www.usmleforum.com/forumdisplay.php?fid=1)
+--- Forum: Step 1 (https://www.usmleforum.com/forumdisplay.php?fid=2)
+--- Thread: exam takers in JAN JOIN HERE - shigatox22 (/showthread.php?tid=638465)
0 - ArchivalUser - 12-19-2011
wats BK virus again?
0 - ArchivalUser - 12-19-2011
Bk is virus is a polyoma virus just like JC virus and both are dsDNA viruses
and rarely cause disease except in Immune compromised patients leading to Nephropathy and hemorhagic cystitis
BKKKK Kidney problems
JC Cerebral problems
0 - ArchivalUser - 12-19-2011
thanks for that
0 - ArchivalUser - 12-19-2011
C3 complement deficiency:
Bacterial infections ( especially encapsulated bacteria )
Increased type III hypersensitivity rxns
C3 deff. increases 3 rxns
0 - ArchivalUser - 12-19-2011
Asplenic patients:
1. spleen is a major site of B cell producing Igs specefically IgM
So asplenic patients will have low IgM which is important for complement activation, thus there be a drop in C3b ( important opsonin ) ----> impaired phagocytosis of encapsulated bacteria which need an opsonin to be phagocytosed
2. Spleen contain phagocytes that will engulf circulating bacteria especially unopsonized. As a result, this will be defective in a spleenic patients.
Net result increased infection by bacteria like Some Killer Have Pretty Nice Capsules
0 - ArchivalUser - 12-19-2011
thanks keep posting
the encapsulated organisms are
salmonella ssp
klebsiella
H.flu
step.Pneumoe
Niserria
Cyptococcus
0 - ArchivalUser - 12-19-2011
count me in ..
0 - ArchivalUser - 12-19-2011
niceeeeeeeee
0 - ArchivalUser - 12-19-2011
@Shiga...wat do you think abt kap physio videos b/w 2010 or 2007.
0 - ArchivalUser - 12-19-2011
hi for cell physio i like the 2007 with the obese guy i think its the first 5 vids n for the rest use kap 2010 u can skip the first chapter if u have a good grasp on the fluid volume compartments n like filtrations pressure ..muscle dyamnics.. stuff like that
but for kap 2010 cardio...resp..renal...GI n endocrine i found very useful esp when combined with material from FA n UW
GL