+- USMLE Forum - Largest USMLE Community (https://www.usmleforum.com)
+-- Forum: USMLE Forum (https://www.usmleforum.com/forumdisplay.php?fid=1)
+--- Forum: Step 1 (https://www.usmleforum.com/forumdisplay.php?fid=2)
+--- Thread: good for those whos exam is near - rizowana (/showthread.php?tid=340380)
0 - ArchivalUser - 10-11-2008
nbme 6 question....
#330457
mrcortti - 08/22/08 12:34
a 76 yo man with a 15 years history of DM 2 and hypertension has had dry skin, market cold intolarance and constipation for 8 months. He is 1.78 cm (5ft 10 in) tall and weighs 85 kg (187 lb), BMI 27 kg/m2. Treatment is started with a full replacement thyroxine T4. This patient is at increased risk of developing which of the following during the first month of therapy?
a- angina pectoris
b-asthma
c-exophthalmos
d- goiter
e- jaundice
Please if know the answer, give me an explanation....THANK YOU>>>
Report Abuse
* Re:nbme 6 question....
#1429119
mrcortti - 08/22/08 12:58
can some body help me with this question..PLEASE>>>>
Report Abuse
* Re:nbme 6 question....
#1429136
rkmehta - 08/22/08 13:27
aa....angina...pt z hypertensive...so must b taking antihypertensive....plus pt z diabetic..so antihypertensive z ane drug xcept beta blocker..so cause reflex tachy.....plus t4.....incrs cardiac demand for o2....angina....
so ll go 4 aaaaaaaa
Report Abuse
* Re:nbme 6 question....
#1429144
drkyhasan - 08/22/08 13:34
agree with rk
aaaaaaaaaaaaa
Report Abuse
* Re:nbme 6 question....
#1429147
orthop - 08/22/08 13:36
Also thyroid hormone senstizes the heart to catecholamine action
Report Abuse
* Re:nbme 6 question....
#1429154
mrcortti - 08/22/08 13:40
thank you guys....i got it
0 - ArchivalUser - 10-11-2008
* nbme 5 s3 Q42
#330202
rsvr - 08/21/08 16:41
44. Clomiphene citrate, follicle-stimulating hormone, and menopausal gonadotropins are administered to a 32-year-old woman to induce folliculogenesis for an in vitro fertilization procedure. The oocytes withing responding antral follicles reinitiate meiotic development as they are released from which of the following stages of meiotic arrest ?
A) 1st meiotic prophase
B) 1st meiotic metaphase
C) 1st meiotic telophase
D) 2nd meiotic prophase
E) 2nd meiotic metaphase
F) 2nd meiotic telophase
Report Abuse
* Re:nbme 5 s3 Q42
#1428220
segxyboy - 08/21/08 17:25
ans e
Report Abuse
* Re:nbme 5 s3 Q42
#1428224
drkyhasan - 08/21/08 17:29
AAAAAAAAA
oocytes are arrested in prophase of 1st meiotic division and just before they ovulate they are in the metaphase of 2nd meiotic division
Report Abuse
* Re:nbme 5 s3 Q42
#1428370
rsvr - 08/21/08 19:57
thanks
0 - ArchivalUser - 10-11-2008
nbme 5 s3 Q4
#330200
rsvr - 08/21/08 16:40
4. A 52-year-old man with alcoholism comes to the physician for a follow-up examination. He has hypertension, type 2 diabetes mellitus, osteoarthritis, and dyslipidemia. Current medications include metformin, glyburide, metoprolol, and sildenafil. Three months ago, he began to follow a diet recommended by the American Heart Association because of an increased serus LDL-cholesterol concentration. He has been adherent with this new regimen. His blood pressure is 135/85 mm Hg. Physical examination shows spider angiomata on the face. Fasting studies show a serum LDL-cholesterol concentration of 148 mg/dL. The physician is considering prescribing pravastatin. This drug should be used with caution because of adverse effects associated with which of the following conditions ?
A) Alcoholism
B) Erectile dysfunction
C) Hypertension
D) Osteoarthritis
E) Type 2 diabetes mellitus
Report Abuse
* Re:nbme 5 s3 Q4
#1428293
target228 - 08/21/08 18:24
A?
Report Abuse
* Re:nbme 5 s3 Q4
#1428297
drkyhasan - 08/21/08 18:29
aaaaaaa
Report Abuse
* Re:nbme 5 s3 Q4
#1428359
rekka - 08/21/08 19:42
A is the correct answer
You can see the features of liver disease in the stem like spider angioma and Pravastatin and the statins in general have hepatotoxic side effects ,the alcoholism should be one big time condition which you should be cautious with
0 - ArchivalUser - 10-11-2008
question about nbme 6
#330251
mrcortti - 08/21/08 18:47
19 yo woman with a 5 year hystory of poorly controlled DM type I gives birth to a plthoric male newborn who weight 5kg (11lb).12 hours later the newborn has hypoglycemia.Which of the following is the most likely cause of this findings in these newborn?
a-increasd fetal pancreatic secretion of insulin
b-increasd fetal produccion of cortisol
c-increased fetal production of GH
d-maternal anti-insuline antybodies, whish cross the placenta
e-maternal insulin,which cross the placenta.
I personally marked a...but I found some answers that marked d...PLEASE give your opinion
Report Abuse
* Re:question about nbme 6
#1428316
target228 - 08/21/08 18:55
I accept A.
Report Abuse
* Re:question about nbme 6
#1428324
drkyhasan - 08/21/08 19:04
A is absolutely right. due to maternal hyperglycemia the fetus secretes more insulin
ur right
Report Abuse
* Re:question about nbme 6
#1428351
rekka - 08/21/08 19:38
D cant be the answer
there is nothing like anti insulin ab in DM so it can't be the answer
A is the correct answer
Report Abuse
0 - ArchivalUser - 10-11-2008
* nbme 1
#330238
target228 - 08/21/08 18:08
An 18-year-old college freshman comes to the clinic at her parents™ urging for evaluation of a 6.8-kg (15-Ib) weight loss. Over the past 4 months, she has had increasing difficulty concentrating on her schoolwork and has begun to miss classes. She avoids friends and often skips meals while watching television alone in her room. She sleeps fitfully and often awakens at 5:00 AM and is unable to go back to sleep. Her weight is currently in the low-normal range. She agrees that something is wrong and feels guilty about her academic performance. Which of the following is the most likely diagnosis?
A) Anorexia nervosa
B) Bulimia
C) Conversion reaction
D) Major depressive disorder
E) Obsessive-compulsive disorder
F) Schizophrenia
why not A?
Report Abuse
* Re:nbme 1
#1428281
pantheon - 08/21/08 18:11
it is aa
Report Abuse
* Re:nbme 1
#1428284
target228 - 08/21/08 18:15
I checked from several forums,which shows it is D.
Report Abuse
* Re:nbme 1
#1428288
pantheon - 08/21/08 18:20
i did it too in nbme n the answer was aa. strange.
Report Abuse
* Re:nbme 1
#1428289
drkyhasan - 08/21/08 18:20
its D because the key there is EARLY MORNING waking which is a major issue with major depression check kaplan notes its there
Report Abuse
* Re:nbme 1
#1428292
pantheon - 08/21/08 18:23
oh ok. thanks target228 n drkyhasan for correcting me... now when i read the q "early morning waking"...makes sense. ofcourse in depression also she can have marked reduction in wt.
Report Abuse
* Re:nbme 1
#1428301
target228 - 08/21/08 18:33
Thanks. I was wondering does anorexia also combine with depression?
Report Abuse
0 - ArchivalUser - 10-12-2008
NBME 5, block 3, Q1
#329948
drtilakpasala - 08/20/08 20:57
A 13 year old girl brough to ER with overdose of diphendydramine. Plasma conc measured hourly for 6 hrs shown.
time----------drug con (ng/mL)
1pm ---------240
2pm ---------202
3pm ---------170
4pm ---------143
5pm ---------120
6pm ---------101
Approximately how long after the first measurement (in hrs) will it take for this patient's plasma conc to drop below 10ng/mL
a. 10
b. 12
c. 16
d. 20
e. 24
f. 30
g. 38
could anybody explain.....
and also let us know what was happening in Q32, block 3, NBME 5.....
regards
Report Abuse
* Re:NBME 5, block 3, Q1
#1426980
rekka - 08/20/08 21:01
Aaaaaaaaaaaaa
Report Abuse
* Re:NBME 5, block 3, Q1
#1426987
drtilakpasala - 08/20/08 21:10
could you please explain how?
i am clearly missing the concept here....
regards
Report Abuse
* Re:NBME 5, block 3, Q1
#1427209
rkmehta - 08/20/08 22:59
here t 1/2 z 4 hrs..see at 1pm 240 n at 5 pm 120....
so on 2nd t1/2 it wud b 60
3rd 30
4th 15
5th 7.5
5 t1/2 needed 2 brinf plasma conc below 10...so 5*4=20...so ans z ddddddddddddddd..
ne thoughts
Report Abuse
* Re:NBME 5, block 3, Q1
#1427493
drtilakpasala - 08/21/08 06:21
cool...sounds good to me....
regards
Report Abuse
* Re:NBME 5, block 3, Q1
#1427534
drkyhasan - 08/21/08 08:31
ok 1st reading is 240
after 5 hours reading is 120 so we know the half life is 5 hours
lets start now.
1st reading 240
5 hours later 120
5 hours more 60
5 hours more 30
5 hours more 15
5 hours more 7.5
so it would take MORE THAN 20 hours for the reading to go BELOW 10 and less than 25 hours. so the answer is EEEEEEEEEEEEEEE 24 hours
not d 20 hours
Report Abuse
* Re:NBME 5, block 3, Q1
#1427535
drkyhasan - 08/21/08 08:32
oooooopppps
half life is 4 hours
answer DDDDDDDDD
my bad
Report Abuse
0 - ArchivalUser - 10-12-2008
nbme q 71
#137204
myusmle - 11/09/06 22:45
A 15-year-old girl has had a sore throat and temperatures to 37.7 C (100 F) for 3 days. Physical examination shows erythematous pharyngeal mucosa and cervical lymphadenopathy. Leukocyte count is 12,000/mm3 with 60% lymphocytes. A slide agglutination test is positive for antibodies against Epstein-Barr virus. This virus is most likely to replicate initially in which of the following cells?
A) Peripheral blood B lymphocytes
B) Peripheral blood monocytes
C) Peripheral blood T lymphocytes
D) Pharyngeal B lymphocytes
E) Pharyngeal monocytes
F) Pharyngeal T lymphocytes
Report Abuse
* Re:nbme q 71
#552147
rmansour - 11/09/06 22:49
PROBABLY A
Report Abuse
* Re:nbme q 71
#552152
myusmle - 11/09/06 22:50
when is ur exam doc
* Re:nbme q 71
#1427298
rekka - 08/21/08 00:29
What is the answer please
Report Abuse
* Re:nbme q 71
#1427308
rizowana - 08/21/08 00:35
answer is a.
0 - ArchivalUser - 10-13-2008
nbme6-q33
#347785
dannyusmle - 10/12/08 13:49
33) Diagram shows....contraction of a blood vessel segment in response to in vitro administration of norepinephrine (NE) before and after drug X is given. After the drug X is given the action of NE is increased (contraction increased).
what is drug X 'sounds very mystiful' ?
a) cocaine
c) isoproterenol (the ans selected)
d) metoprolol
e)phenoxybenzamine
f)reserpine
g)tyramine
could someone answers and explains plzzzzzzz
Report Abuse
* Re:nbme6-q33
#1507004
oldhakim - 10/12/08 14:16
a.......b/c it blocks reuptake
Report Abuse
* Re:nbme6-q33
#1507012
dannyusmle - 10/12/08 14:25
oldhakim, cocaine blocks reuptake so it incr NE..., but tyramine also incr NE because it is a releaser. wat do you think?
Report Abuse
* Re:nbme6-q33
#1507020
digitalis - 10/12/08 14:28
hello,
answer is C because isoproterenol is a beta 1 and beta 2 agonist where as norepinephrine is beta 2 agnist.... It is epinephrine which is non selective adrenergic agonist.
cocaine blocks dopamine reuptake receptors... does not have anything to do with beta 1 or 2 receptors...
hope this clears up the things!
thanks
Report Abuse
* Re:nbme6-q33
#1507078
dannyusmle - 10/12/08 14:54
digitalis
NE does not have beta2 agonic effect, and it causes vasocontriction because of alpha1 effect. if we give isoproterenol (beta1 and beta2 agonist), it will cause vasodilation via beta2 effect, so it will decrease the vasocontriction effect og NE
Correct me if I am wrong
Report Abuse
* Re:nbme6-q33
#1507110
dannyusmle - 10/12/08 15:21
any orther ideas
Report Abuse
* Re:nbme6-q33
#1507132
drstrider - 10/12/08 15:42
yeah agreed wit u dannyusmle NE hs no B2 effect.
not sure but i guess invitro prep has no innervation..so no syanpse stuff so options cocaine n tyramine r out..phenoxybenzamine is alpha blocker it cant b,metprolol is b1 selective is it cant b
left wit iso...but how cum we see a increase in contraction after iso?
bro itz just a guess from my side..i came to iso by exclusion..may b i'm wrong..letz c wat others have to say
Report Abuse
* Re:nbme6-q33
#1507323
dannyusmle - 10/12/08 17:43
any one can explain this question convincingly?
thanks alot
Report Abuse
* Re:nbme6-q33
#1507345
oldhakim - 10/12/08 18:00
it deals with drug x which increases NE action either by realese or prevents alpha2 induced inhibition of NE release........but i dont think you see tyramine derived pressor response in non MAO inhibited nerve terminals which is not significant.
0 - ArchivalUser - 10-13-2008
NBME 1 form 2 question
#347505
letsallget99 - 10/11/08 15:31
800 motor vehicle accidents occurred over 2 years in a city of 600,000. 600 of the accidents were alcohol related. In this period 400 deaths were due to motor vehicle collisions, of which 75% were alcohol related. What is the 1 year incidence of alcohol related motor vehicle fatalities in the community?
The answer they have listed is 300 per 600,000.....I don't understand how this could be correct.....They are asking for 1 year incidence in a 2 year study....Wouldn't you take the 300 deaths over the 2 years and divide by 2 to get 150 per 600,000???? Can anyone explain?
Report Abuse
* Re:NBME 1 form 2 question
#1505937
letsallget99 - 10/11/08 17:02
????
Report Abuse
* Re:NBME 1 form 2 question
#1506240
rizowana - 10/11/08 22:00
2 yrs incidence of alcohol related motor vehicle fatality is 300 according to the calculation
for the arguments sake if we assume that each year exactly the same number of alcohol related accidents occur( which is very unlikely), then we can divide the number 300 with 2 and get the answer 150.
this question is very confusing question. i am not surprised. americans are not good at math LOL, its us, the immigrants do all the math there. ha ha ha
Report Abuse
* Re:NBME 1 form 2 question
#1506411
letsallget99 - 10/12/08 00:22
LOL thanks Rizowana....I happen to be American though...haha.....I did go away to another country for medical school so I guess that is where I acquired my math skills......It still doesn't make sense to me...They did give an option choice saying cannot be caclulated....I assume that would be the correct choice given they are asking for 1 year incidence in a time frame of 2 years....Just doesn't seem feasible...
Report Abuse
* Re:NBME 1 form 2 question
#1506917
letsallget99 - 10/12/08 13:20
No other people have an opinion???
Report Abuse
* Re:NBME 1 form 2 question
#1506919
pankyash - 10/12/08 13:21
i think cant be calculated..
0 - ArchivalUser - 10-13-2008
* help, NBME form5 section 1, q4
#347545
qqting - 10/11/08 18:14
a 65- year old man with long history of smoking and shortness of breath has arterial oxygen saturation of 84%. This patient's inability to maintain adequate tissue O2 will most likely lead to increased production of which of the following in RBCs?
a. 2, 3 BPG
b. EPO
c. ketone bodies
d. lactate
e. methmoglobin
f. NADPH
due to reduced SaO2, RBC should be lack of enough ATP, so it should generate more lactate. But other people also choose a or b. so what is the right answer? and why?
thank you.
Report Abuse
* Re:help, NBME form5 section 1, q4
#1506381
qqting - 10/11/08 23:52
anyone has any idea?
Report Abuse
* Re:help, NBME form5 section 1, q4
#1506479
demi - 10/12/08 01:46
Dec Ph,INC 23 BPG lead to increased O2 delivery to tissues i guess and this Q is asking -patient's inability to maintain adequate tissue O2 .
Report Abuse
* Re:help, NBME form5 section 1, q4
#1506899
pankyash - 10/12/08 13:12
is A for sure.. bcoz the Q is asking about production inc in the RBC.. cant be B.. EPO is not formed in RBCs.. and lactate wont help in increasing tissue O2..
Report Abuse