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Phenytoin - samideb12 - Printable Version

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Phenytoin - samideb12 - ArchivalUser - 12-06-2011

Is phenytoin given to a 12 years old pt ?


0 - ArchivalUser - 12-06-2011

i think so DOSAGE IN PAEDIATRICS:
Loading dose in an emergency:
15-20mg/kg (max 1.5gm) IV over 1 hour.
Initial maintenance, oral or IV:
2mg/kg 12 hourly (preterm); 3mg/kg 12 hourly (1st week of life), 8 hourly (2wk-4yr), 12 hourly (5-12 yr); 2mg/kg (usual max 100mg) 8 hourly (12 yrs)
remember also this -Drugs whose efficacy is impaired by phenytoin include:
corticosteroids, warfarin, frusemide, oral contraceptives, rifampin, and theophylline


0 - ArchivalUser - 12-06-2011

the only C/I i remem- is a known teratogen. The syndrome consists of craniofacial anomalies (broad nasal bridge, cleft lip and palate, microcephaly) and a mild form of mental retardation (average IQ=71).


0 - ArchivalUser - 12-06-2011

Thank you for explanation.I thought that phenobarb is preferred .