[sickle cell] - rodion

[ArchivalUser]

42.An 8-year-old boy with sickle cell disease presents with left leg pain and a high fever. He has been refusing to walk since yesterday. On physical examination, his temperature is 39.8 C (103.6 F), blood pressure is 122/68 mm Hg, pulse is 102/min, and respirations are 20/min. His left femur is tender to palpation 3 cm above the left knee, and there is marked soft tissue swelling. A plain film of his left leg is normal. A bone scan shows increased uptake around the metaphysis of the left femur. Which of the following is the most likely pathogen?
a)Escherichia coli
b)Haemophilus influenzae
c)Salmonella
d)Staphylococcus aureus
e)Streptococcus pneumoniae

[ArchivalUser]

C is the ans

[ArchivalUser]

D

[ArchivalUser]

i agree D....

[ArchivalUser]

D cause staph aureus is the MCC of osteomyleitis... but if there would have been no staph aureus in the option then it would be salmonells as it is the MC org for osteomyelitis in sickle cell pt

[ArchivalUser]

It's C. Staph is the most common organism causing osteomyelitis, however salmonela are the most common organism (up to 70%) causing osteomyelytis in patients with SCD, Staph accounts only for less than 25%. UW has almost identical q. it's ID#1504 and in it's explanation objective they provide reference books.

[ArchivalUser]

)Salmonella

[ArchivalUser]

C. The mechanism may be due to the autosplenectomy.

[ArchivalUser]

answer is D with the 'usual' reasoning