09-29-2006, 08:57 PM
70 yr old woman has increasing weakness, weight loss, generalized lymph node enlargement, and hepatosplenomegaly. Laboratory studies show absolute lymphocytosis with the majority of cells being CD 5+. The patient also has a mild antiglobulin-positive hemolytic anemia. Karyotype is normal. Which is the most likely diagnosis?
a. Acute lymphoblastic leukemia
b. Acute promyelocytic leukemia
c. Chronic lymphocytic leukemia
d. Chronic myeloid leukemia
e. Fanconi™s anemia
f. Hairy cell leukemia
g. Myelodysplastic syndrome
h. Myeloid metaplasia with myelofibrosis
i. Polycythemia vera
a. Acute lymphoblastic leukemia
b. Acute promyelocytic leukemia
c. Chronic lymphocytic leukemia
d. Chronic myeloid leukemia
e. Fanconi™s anemia
f. Hairy cell leukemia
g. Myelodysplastic syndrome
h. Myeloid metaplasia with myelofibrosis
i. Polycythemia vera