decreasing visual acuity - proteus

[ArchivalUser]

A 28-year-old male has noticed decreasing visual acuity in his left eye for the past several weeks. Two months later, he is completely blind in his left eye. He has no other symptoms for 3 months but then notices decreasing visual acuity in his right eye. He loses vision in his right eye over several weeks time. His mother tells him that there is a family history of blindness. This condition most likely has which of following modes of inheritance?

A. Autosomal dominant
B. Autosomal recessive
C. X-linked recessive
D. X-linked dominant
E. Mitochondrial inheritance

[ArchivalUser]

E.

[ArchivalUser]

Leber's Optic Neuropathy?

[ArchivalUser]

ee.

[ArchivalUser]

YOU ARE ALL CORRECT HERE
Choice (E) is the correct answer. Leber's optic neuropathy is a disease characterized by bilateral subacute optic neuropathy and is caused by mitochondrial gene mutations. Mothers pass the condition to their offspring. Males are affected more often than females, though it is not understood why. The condition usually presents in males during their twenties or thirties. Vision is lost in one eye over a period of weeks. Several months later, vision is lost in the other eye. There is, unfortunately, no cure for the disease. The other choices are incorrect.