03-08-2010, 06:20 AM
A 44-year-old woman, gravida 4, para 3, at 8 weeks' gestation comes to the physician for her
first prenatal visit. She has mild nausea and vomiting but no other complaints. Her obstetric
history is significant for three full-term, normal vaginal deliveries of normal infants. She has no
medical or surgical history and takes no medications. Physical examination reveals an
8-week-sized uterus, but is otherwise unremarkable. She wishes to have chromosomal testing
of the fetus and wants to have chorionic villus sampling performed, as she did with her last
pregnancy. Compared with amniocentesis, chorionic villus sampling may place the patient at
greater risk for which of the following?
A. Fetal Down syndrome
B. Fetal limb defects
C. Fetal neural tube defects
D. Maternal sepsis
E. Mid-second-trimester abortion
first prenatal visit. She has mild nausea and vomiting but no other complaints. Her obstetric
history is significant for three full-term, normal vaginal deliveries of normal infants. She has no
medical or surgical history and takes no medications. Physical examination reveals an
8-week-sized uterus, but is otherwise unremarkable. She wishes to have chromosomal testing
of the fetus and wants to have chorionic villus sampling performed, as she did with her last
pregnancy. Compared with amniocentesis, chorionic villus sampling may place the patient at
greater risk for which of the following?
A. Fetal Down syndrome
B. Fetal limb defects
C. Fetal neural tube defects
D. Maternal sepsis
E. Mid-second-trimester abortion