08-25-2010, 05:58 PM
A male infant is born at term to a 22-year-old African-American primigravida, blood group A, Rh (D)+. The prenatal course was complicated, with asymptomatic bacteriuria and mild hypertension without proteinuria in the third trimester. The newborn demonstrates yellow sclerae twelve hours after birth. He is blood group O, Rh (D)+. The total bilirubin level is 7 mg/dl, with the unconjugated bilirubin predominantly elevated. Coombs test is negative. The mother says that there is 'a kind of blood disease running in the family.' Which of the following is the most likely cause of this patient's jaundice?
Options
1. Sickle cell anemia
2. HbS-HbC disorder
3. Beta-thalassemia
4. G-6-PD-deficiency anemia
5. Physiologic jaundice
Options
1. Sickle cell anemia
2. HbS-HbC disorder
3. Beta-thalassemia
4. G-6-PD-deficiency anemia
5. Physiologic jaundice