02-15-2011, 04:09 PM
SGLT--??
BMPR2--??
BMPR2--??
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where its used----q - sodium
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02-15-2011, 04:24 PM
SGLT--Sodium Glucose Luminal Transporter---> you know the full form, you know the function--- we all know that sodium and glucose are best friends and all ways move in together ( the logic behind oral rehydration solution)----> and where ever there is luminal structures these are present--- 1) lumen of the gut 2) lumen of nephrons
BMPR2-- again, Bone Morphogenic Protein Receptor type 2---Osteogenesis, cell growth etc 2nd one Unlikely questions on the USMLE! its too complex!
02-15-2011, 04:27 PM
it sucks men or woman i dont know who u r ,these things kinda dont stay long in this consolidated brain.
but anyways---SGLT-1 (Na dependent) for uptake of glucose and galactose. BMPR-2 --normal function is to inhibit vascular smooth muscle proliferation,if inactivated by a mutation its the cause of PRIMARY PULMONARY HTN.--POOR PROGNOSIS.
02-15-2011, 04:34 PM
BMPR2 is known as the PAH gene (pulmonary arterial hypertension) because mutations in BMPR2 are related to development of PAH.
The source I read states that loss of function of BMPR2 is associated with endothelial cell apoptosis, which could be an initiating factor in the process of developing PAH. |
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