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question,,,?????? - usmle113
#1
in hip replacement surgery,,,we give warfarin or LMWH to pts to prevent DVT,,,,
but how that pt,s vessels cut in surgery will clot if we give him heparin after surgery,,,
??????????
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#2
Hi


Timing and duration of prophylactic agents has also been determined to have a significant effect the development of DVT. Early prophylaxis in surgical patients with LMWH has been associated with significant reductions in postoperative venous thrombosis. Studies have shown that initiation of therapy within 8 hours of surgery has the greatest effect . Additional recommendations by the ACCP for extended out-of-hospital prophylaxis have been made based on multiple randomized studies that have demonstrated an additional 7-10 days of anticoagulation decrease venous thrombosis rates WITHOUT major bleeding issues.

Good luck

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