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If u infuse 3% hypertonic saline, what do u expect the plasma osmolarity and ADH levels to be....?
A. Posm Increase, ADH = Decrease
B. Posm --> Decrease, ADH = Increase
C. Posm --> Increase, ADH = Increase
D. WTF ???
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OK I understand how Posm increases, but how ADH increase ???
Isn't it supposed to decrease since u r Loading fluids into the person ???
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hyperosmolarity is best stimulant for ADH
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ADH regulation - secreted in response to increased plama osmolarity and decreased blood volume.
hypertonic saline - increased plasma osmolarity - increased ADH
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Oh ok...So increase in Sodium, which means increase in plasma osmolarity = increase in ADH release !!
Got it !
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ADH maintain the osmolarity and aldosterone THE VOLUME
BUT when there is hypovolumia THEY BOTH WORK TO INCREASE THE VOLUME