Question..............2 - psychmledr

[ArchivalUser]

With exposure to anticancer agents, tumor cells can become resistant to those agents.
They do so by expression of a surface glycoporotein having which of the following functions:

A. Tyrosine kinase-coupled receptor
B. Adenylate cyclase-coupled receptor
C. Cell adhesion molecule
D. Transmembrane ion channel
E. ATP-dependent transporter

[ArchivalUser]

Typo: *glycoprotein

[ArchivalUser]

Good question I would guess:

AAA : because of growth factor association?

[ArchivalUser]

eee

[ArchivalUser]

EE

[ArchivalUser]

E.

[ArchivalUser]

Yes, "E" is correct

The human multidrug resistance (MDR1) gene codes for P-glycoprotein, a transmembrane ATP-dependent efflux pump protein that has a broad specificity for hydrophobic compounds.
This protein can both reduce influx of drugs into the cytosol and can increase efflux from the cytosol, thereby preventing the action of chemotherapeutic agents.

[ArchivalUser]

nice question!!! thank you )

[ArchivalUser]

You're welcome, zen786

[ArchivalUser]

very nice Q ,Thank you