06-14-2012, 08:06 PM
NBME 12 answers
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section 1
1. BAEDF
6. EBBCD
11. BBAFE
16. BADAA
21. AAAEA
26. CECAC
31. AFBBC
36. EADAD
41. DEDCC
46. CEGDF
---------------------------------------------
section 2
1. EBAAA
6. CEEFC
11. CBDBD
16. DCCEF
21. AACEC
26. EDEEB
31. CAADD
36. EBDDC
41. ADDCD
46. ADFBC
-------------------------------------------
section 3
1. ECAEE
6. BBCDC
11. BAEBA
16. CACCD
21. DEEDB
26. CCEFB
31. BADDC
36. CDDBA
41. AADBB
46. AADDA
-----------------------------------------
section 4
1. AAEDE
6. BDECB
11. DADCC
16. ACBEE
21. CADAB
26. CDADC
31. CECBC
36. CADAC
41. DDDDB
46. DDCAF
correction
26.D
29.C
NBME 12 SECTION 01
1 B
2 A
3 I do not know (B is wrong for sure), may be E because the doctor should be sure that his patient want to quite before giving him advices ?? who knows??
4 D (selectin loose binding on endothelial cells.. See FA pathology section)
5 F (riketssia Rx tetracycline)
6 E
7 B (horner syndrome)
8 B (avascular necrosis--medial femoral circumflex = memorisation)
9 C (why not anticholinergic?? cause vagus stimulate G cell by GRP= gastrin releasing petptide, not ACTh see FA gastroenterlogy section).
10 D spherocytosis. not pale centre in RBC+ unconjugated bilirubin
11 B (vinblastin+ vincristine + paclitaxel work on microtubules first two decreasepolymerisation , taxols does not let microtubules break down so the cell is fixed in metaphase I think
)
12 B
13 B (avoid eye contact = kind of autist but normal inteligence, asperger is kind of autism )
14 F not sure( NNT = 1 / (Control Event Rate) - (Experimental Event Rate) -->
1/(0.023-0,013)
15 E
16 A
17 A
18 D (cigarette smokes in winter so i guess windows are close CO poisening)
19 A parietal cell destruction ---> intrinsic factor low ---> megaloblastic anemia.
20 A (not sure , D is wrong for sure)
21 A (klinfelter)
22 E
23 A (it"s an antagonist of acethylcholine uses in asthma)
24 E
25 A leuprilide continous stimulation of gonad lead to decrease secretion of sexe hormone (androgene is our cible in this case)
26 C
27 E (first see PH, is decreased means acidosis, she is hyperventilation means respiration started the compensatory process, after 2 days I think, the kidney will start also puting HCO3 in the blood and sectreting with the urine H+ .. NH4CL is a titrable acide means like a boat to put H+ in to send out of the body)
28 mystery question for me I could not even know the diagnosis (A is wrong) may be C just because intestine are involved, no rational reason , please hepl to figure out the diagnosis.
29 C 2 isoenzyme means the work on the same familly of molecules . enzyme 1 is faster (300) than enzyme 2 (30) . why ? becasue the affinity of enzyme 1 is greater than enzyme 2. mmeans you need less amount of enzyme 1 then enzyme 2 (Km)
30 C
31 A
32 F (it is about apoptosis BCL2/Akt. you can google it but I am not sure)
33 B almost sure (external validity means can you generate the result to all patients in this study the reaaly choose a very representative population with inssurance and without, different gendre different socioeconomic status. so you ac apply the result of the study on all type of patients).
34 B (infliximab is MAB for TNF)
35 C (I think in spontaneus pneumothorax you will not hear respiration at all and why will be wheezes?)
36 E (transpantation ---> CMV= virus = T lymphocytes)
37 A
38 may be D (C is wrong) 3 years 20 words: there is a prob here. MRI is expensive to start with I think :-)
39 A
40 D angiotensine converting enzyme is synthesises in the lung (I think the buzz word here is directly mediated may be...)
41 D
42 E (it is not about humerus or shoulder
o B or E she did not fall just grabbed hand and no edema)
43 D not sure ( portal hypertention )
44 C (nitroglycerine dilate veins ans arteriol via NO)
45 C alzheimer
46 C
47 E (no change after desmopressin )
48 F (weekness = motor, atrophy = lower MN . left =left decussation of pyramid al tract is in the medullae)
49 D (no mitosis no necrosis+ most common GYN tumor )
50 F (steroid liposoluble acces to the cell and the nucleous).
NBME 12 SECTION 02
1 E Normal renal architecture (tubular re-epithelization after ATN)
2 B E-cadherin
3 A Bromocriptin (increase Dopamine=Prolactin inhibitor)
4 E Serum TG will decrease (increase in HPL)
5 A Blockade of leukotriene receptor
6 C 4 prevalent cases in Dec. 31
7 E UDP glucuronosyltransferase deficiency
8 E Leptin
9 C? hypertrophic cardiomyopathy leading to pulmunary stenosis?
10 C malrotation (tip Chest x-ray + abrupt onset of pain)
11? B is wrong
12 B Heart failure (classic CHF)
13 D Norepinephrine
14 B "I see some bruising..."
15 D Improved cellular responsiveness to insulin
16 D Failure of urogenital folds to fuse
17 C Nonseminoma neoplasm
18 C Lysosome(lysosomal disease)
19 E Myopathy and hepatotoxicity
20 F Renal agenesis
21? C is wrong (maybe A?)
22 A Early diastole (diastole is when coronary artery flow is maximum,I answered C and it's wrong)
23 C Hypertensive retinopathy
24 E Renal cell CA
25 C Phrenic nerve
26 E Partial agonism
27 D? Reassortment of hemagglutinin? or E? (F is wrong)
28 E Hypertrophic cardiomyopathy
29 E Rubella (THORCH)
30 B Indinavir?
31 C Mebendazole (swimmers itch caused by non-human schistosoma)
32 ? (E is wrong)
33? (B is wrong)
34 D Placement of external defibrillators...(can see fastest result)
35 D Subjects with no evidence of colonic polyposis
36 E increase in Hgb F conc.
37 B Fc receptor
38 C Oligodentdrocytes (MS)
39 C Regeneration of muscle fibers (showing fiber grouping)
40 B Absent pain proximal fibula, Present pain distal fibula, Dorsiflextion 0/5, Plantar flexion
4/5, Achilles reflex 1+
41 A (cuneate, gracile and Trigeminal Nerve location)
42 D Type IV(delayed)
43 ? maybe A (B is wrong)
44 C Decrease in Median, Unchanged Mode, Decreased Mean
45 D Stool assay for toxin (C. deficile)
46 A Autosomal dominant with variable expressivity
47 D Vit. C
48 F wearing a helmet
49 B Chlamydia trachomatis (silver nitrate didn't prevent, intracytoplasmic inclusions)
50 C Multiple myeloma (osteolytic bone lesions and rouleaux formation
NBME 12 SECTION 03
1 E Normal renal architecture (tubular re-epithelization after ATN)
2 B E-cadherin
3 A Bromocriptin (increase Dopamine=Prolactin inhibitor)
4 E Serum TG will decrease (increase in HPL)
5 A Blockade of leukotriene receptor
6 C 4 prevalent cases in Dec. 31
7 E UDP glucuronosyltransferase deficiency
8 E Leptin
9 C? hypertrophic cardiomyopathy leading to pulmunary stenosis?
10 C malrotation (tip Chest x-ray + abrupt onset of pain)
11? B is wrong
12 B Heart failure (classic CHF)
13 D Norepinephrine
14 B "I see some bruising..."
15 D Improved cellular responsiveness to insulin
16 D Failure of urogenital folds to fuse
17 C Nonseminoma neoplasm
18 C Lysosome(lysosomal disease)
19 E Myopathy and hepatotoxicity
20 F Renal agenesis
21? C is wrong (maybe A?)
22 A Early diastole (diastole is when coronary artery flow is maximum,I answered C and it's wrong)
23 C Hypertensive retinopathy
24 E Renal cell CA
25 C Phrenic nerve
26 E Partial agonism
27 D? Reassortment of hemagglutinin? or E? (F is wrong)
28 E Hypertrophic cardiomyopathy
29 E Rubella (THORCH)
30 B Indinavir?
31 C Mebendazole (swimmers itch caused by non-human schistosoma)
32 ? (E is wrong)
33? (B is wrong)
34 D Placement of external defibrillators...(can see fastest result)
35 D Subjects with no evidence of colonic polyposis
36 E increase in Hgb F conc.
37 B Fc receptor
38 C Oligodentdrocytes (MS)
39 C Regeneration of muscle fibers (showing fiber grouping)
40 B Absent pain proximal fibula, Present pain distal fibula, Dorsiflextion 0/5, Plantar flexion
4/5, Achilles reflex 1+
41 A (cuneate, gracile and Trigeminal Nerve location)
42 D Type IV(delayed)
43 ? maybe A (B is wrong)
44 C Decrease in Median, Unchanged Mode, Decreased Mean
45 D Stool assay for toxin (C. deficile)
46 A Autosomal dominant with variable expressivity
47 D Vit. C
48 F wearing a helmet
49 B Chlamydia trachomatis (silver nitrate didn't prevent, intracytoplasmic inclusions)
50 C Multiple myeloma (osteolytic bone lesions and rouleaux formation
NBME 12 SECTION 04
--------------------------------------
section 1
1. BAEDF
6. EBBCD
11. BBAFE
16. BADAA
21. AAAEA
26. CECAC
31. AFBBC
36. EADAD
41. DEDCC
46. CEGDF
---------------------------------------------
section 2
1. EBAAA
6. CEEFC
11. CBDBD
16. DCCEF
21. AACEC
26. EDEEB
31. CAADD
36. EBDDC
41. ADDCD
46. ADFBC
-------------------------------------------
section 3
1. ECAEE
6. BBCDC
11. BAEBA
16. CACCD
21. DEEDB
26. CCEFB
31. BADDC
36. CDDBA
41. AADBB
46. AADDA
-----------------------------------------
section 4
1. AAEDE
6. BDECB
11. DADCC
16. ACBEE
21. CADAB
26. CDADC
31. CECBC
36. CADAC
41. DDDDB
46. DDCAF
correction
26.D
29.C
NBME 12 SECTION 01
1 B
2 A
3 I do not know (B is wrong for sure), may be E because the doctor should be sure that his patient want to quite before giving him advices ?? who knows??
4 D (selectin loose binding on endothelial cells.. See FA pathology section)
5 F (riketssia Rx tetracycline)
6 E
7 B (horner syndrome)
8 B (avascular necrosis--medial femoral circumflex = memorisation)
9 C (why not anticholinergic?? cause vagus stimulate G cell by GRP= gastrin releasing petptide, not ACTh see FA gastroenterlogy section).
10 D spherocytosis. not pale centre in RBC+ unconjugated bilirubin
11 B (vinblastin+ vincristine + paclitaxel work on microtubules first two decreasepolymerisation , taxols does not let microtubules break down so the cell is fixed in metaphase I think
)12 B
13 B (avoid eye contact = kind of autist but normal inteligence, asperger is kind of autism )
14 F not sure( NNT = 1 / (Control Event Rate) - (Experimental Event Rate) -->
1/(0.023-0,013)
15 E
16 A
17 A
18 D (cigarette smokes in winter so i guess windows are close CO poisening)
19 A parietal cell destruction ---> intrinsic factor low ---> megaloblastic anemia.
20 A (not sure , D is wrong for sure)
21 A (klinfelter)
22 E
23 A (it"s an antagonist of acethylcholine uses in asthma)
24 E
25 A leuprilide continous stimulation of gonad lead to decrease secretion of sexe hormone (androgene is our cible in this case)
26 C
27 E (first see PH, is decreased means acidosis, she is hyperventilation means respiration started the compensatory process, after 2 days I think, the kidney will start also puting HCO3 in the blood and sectreting with the urine H+ .. NH4CL is a titrable acide means like a boat to put H+ in to send out of the body)
28 mystery question for me I could not even know the diagnosis (A is wrong) may be C just because intestine are involved
, no rational reason , please hepl to figure out the diagnosis.29 C 2 isoenzyme means the work on the same familly of molecules . enzyme 1 is faster (300) than enzyme 2 (30) . why ? becasue the affinity of enzyme 1 is greater than enzyme 2. mmeans you need less amount of enzyme 1 then enzyme 2 (Km)
30 C
31 A
32 F (it is about apoptosis BCL2/Akt. you can google it but I am not sure)
33 B almost sure (external validity means can you generate the result to all patients in this study the reaaly choose a very representative population with inssurance and without, different gendre different socioeconomic status. so you ac apply the result of the study on all type of patients).
34 B (infliximab is MAB for TNF)
35 C (I think in spontaneus pneumothorax you will not hear respiration at all and why will be wheezes?)
36 E (transpantation ---> CMV= virus = T lymphocytes)
37 A
38 may be D (C is wrong) 3 years 20 words: there is a prob here. MRI is expensive to start with I think :-)
39 A
40 D angiotensine converting enzyme is synthesises in the lung (I think the buzz word here is directly mediated may be...)
41 D
42 E (it is not about humerus or shoulder
o B or E she did not fall just grabbed hand and no edema)43 D not sure ( portal hypertention )
44 C (nitroglycerine dilate veins ans arteriol via NO)
45 C alzheimer
46 C
47 E (no change after desmopressin )
48 F (weekness = motor, atrophy = lower MN . left =left decussation of pyramid al tract is in the medullae)
49 D (no mitosis no necrosis+ most common GYN tumor )
50 F (steroid liposoluble acces to the cell and the nucleous).
NBME 12 SECTION 02
1 E Normal renal architecture (tubular re-epithelization after ATN)
2 B E-cadherin
3 A Bromocriptin (increase Dopamine=Prolactin inhibitor)
4 E Serum TG will decrease (increase in HPL)
5 A Blockade of leukotriene receptor
6 C 4 prevalent cases in Dec. 31
7 E UDP glucuronosyltransferase deficiency
8 E Leptin
9 C? hypertrophic cardiomyopathy leading to pulmunary stenosis?
10 C malrotation (tip Chest x-ray + abrupt onset of pain)
11? B is wrong
12 B Heart failure (classic CHF)
13 D Norepinephrine
14 B "I see some bruising..."
15 D Improved cellular responsiveness to insulin
16 D Failure of urogenital folds to fuse
17 C Nonseminoma neoplasm
18 C Lysosome(lysosomal disease)
19 E Myopathy and hepatotoxicity
20 F Renal agenesis
21? C is wrong (maybe A?)
22 A Early diastole (diastole is when coronary artery flow is maximum,I answered C and it's wrong)
23 C Hypertensive retinopathy
24 E Renal cell CA
25 C Phrenic nerve
26 E Partial agonism
27 D? Reassortment of hemagglutinin? or E? (F is wrong)
28 E Hypertrophic cardiomyopathy
29 E Rubella (THORCH)
30 B Indinavir?
31 C Mebendazole (swimmers itch caused by non-human schistosoma)
32 ? (E is wrong)
33? (B is wrong)
34 D Placement of external defibrillators...(can see fastest result)
35 D Subjects with no evidence of colonic polyposis
36 E increase in Hgb F conc.
37 B Fc receptor
38 C Oligodentdrocytes (MS)
39 C Regeneration of muscle fibers (showing fiber grouping)
40 B Absent pain proximal fibula, Present pain distal fibula, Dorsiflextion 0/5, Plantar flexion
4/5, Achilles reflex 1+
41 A (cuneate, gracile and Trigeminal Nerve location)
42 D Type IV(delayed)
43 ? maybe A (B is wrong)
44 C Decrease in Median, Unchanged Mode, Decreased Mean
45 D Stool assay for toxin (C. deficile)
46 A Autosomal dominant with variable expressivity
47 D Vit. C
48 F wearing a helmet
49 B Chlamydia trachomatis (silver nitrate didn't prevent, intracytoplasmic inclusions)
50 C Multiple myeloma (osteolytic bone lesions and rouleaux formation
NBME 12 SECTION 03
1 E Normal renal architecture (tubular re-epithelization after ATN)
2 B E-cadherin
3 A Bromocriptin (increase Dopamine=Prolactin inhibitor)
4 E Serum TG will decrease (increase in HPL)
5 A Blockade of leukotriene receptor
6 C 4 prevalent cases in Dec. 31
7 E UDP glucuronosyltransferase deficiency
8 E Leptin
9 C? hypertrophic cardiomyopathy leading to pulmunary stenosis?
10 C malrotation (tip Chest x-ray + abrupt onset of pain)
11? B is wrong
12 B Heart failure (classic CHF)
13 D Norepinephrine
14 B "I see some bruising..."
15 D Improved cellular responsiveness to insulin
16 D Failure of urogenital folds to fuse
17 C Nonseminoma neoplasm
18 C Lysosome(lysosomal disease)
19 E Myopathy and hepatotoxicity
20 F Renal agenesis
21? C is wrong (maybe A?)
22 A Early diastole (diastole is when coronary artery flow is maximum,I answered C and it's wrong)
23 C Hypertensive retinopathy
24 E Renal cell CA
25 C Phrenic nerve
26 E Partial agonism
27 D? Reassortment of hemagglutinin? or E? (F is wrong)
28 E Hypertrophic cardiomyopathy
29 E Rubella (THORCH)
30 B Indinavir?
31 C Mebendazole (swimmers itch caused by non-human schistosoma)
32 ? (E is wrong)
33? (B is wrong)
34 D Placement of external defibrillators...(can see fastest result)
35 D Subjects with no evidence of colonic polyposis
36 E increase in Hgb F conc.
37 B Fc receptor
38 C Oligodentdrocytes (MS)
39 C Regeneration of muscle fibers (showing fiber grouping)
40 B Absent pain proximal fibula, Present pain distal fibula, Dorsiflextion 0/5, Plantar flexion
4/5, Achilles reflex 1+
41 A (cuneate, gracile and Trigeminal Nerve location)
42 D Type IV(delayed)
43 ? maybe A (B is wrong)
44 C Decrease in Median, Unchanged Mode, Decreased Mean
45 D Stool assay for toxin (C. deficile)
46 A Autosomal dominant with variable expressivity
47 D Vit. C
48 F wearing a helmet
49 B Chlamydia trachomatis (silver nitrate didn't prevent, intracytoplasmic inclusions)
50 C Multiple myeloma (osteolytic bone lesions and rouleaux formation
NBME 12 SECTION 04