03-17-2016, 11:31 AM
A 45-year-old woman presents with a 2-month history of fatigue and recurrent fever. She also complains of tenderness below the right costal margin and dark urine. Physical examination reveals jaundice and mild hepatomegaly. The serum is positive for hepatitis B virus antigen. Which of the following best describes the mechanism of indirect virus-mediated hepatocyte cell death in this patient?
(A) Accumulation of abnormal cytoplasmic proteins
(B) Immune recognition of viral antigens on the cell surface
© Generation of cytoplasmic free radicals
(D) Impaired plasma membrane Na+/K+ ATPase activity
(E) Interference with cellular energy generation
(A) Accumulation of abnormal cytoplasmic proteins
(B) Immune recognition of viral antigens on the cell surface
© Generation of cytoplasmic free radicals
(D) Impaired plasma membrane Na+/K+ ATPase activity
(E) Interference with cellular energy generation