04-11-2018, 06:34 PM
The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome.
https://www.creativebiomart.net/symbolsearch_CD40LG.htm
https://www.creativebiomart.net/symbolsearch_CD40LG.htm