Posts: 3,675,937
Threads: 734,344
Joined:
Sep 2021
Reputation:
5
azaaza, great findings. yes, the answer is 14L
MALENA, the calculation is very simple since Mannitol goes to everywhere extracellularly,
9g/ (65mg/100ml)===14 L
Posts: 3,675,937
Threads: 734,344
Joined:
Sep 2021
Reputation:
5
quanser
how do we know how much of that 9g of mannitol is lost in urine... since it is freely filterd- can not account all that 9gr to be in extracellular fluid
Posts: 3,675,937
Threads: 734,344
Joined:
Sep 2021
Reputation:
5
my bad.
yes, I already included that factor to simplify the q. the injection amount is 10g, and 1 g is lost in the urine before reaching the stated plasma concentration.
My point for this q is to let everybody know manitol goes to interstitial compartment, it does not only stay in the blood vessel, which may be commonly mistaken.
Posts: 3,675,937
Threads: 734,344
Joined:
Sep 2021
Reputation:
5
oh ok..
yeah then did not need to do long way like I did
Posts: 3,675,937
Threads: 734,344
Joined:
Sep 2021
Reputation:
5
thx for this concept.... all this while even i thought Mannitol stays in the plasma only!
Posts: 3,675,937
Threads: 734,344
Joined:
Sep 2021
Reputation:
5
REMEMBER THE FORMULA
C X V= A
C CONCENTRATION
V VOLUME
A AMOUNT
V WILL BE A/C AND IT GIVE YOU 13.5 VER CLOSE TO 14 SO THE ANSWER WILL 14 LITERS