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Renal excretion K+ in acute vs chronic acidosis?? - longislandmd2b

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Renal excretion K+ in acute vs chronic acidosis?? - longislandmd2b
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#1
04-13-2007, 12:38 AM
Can anyone explain the MECHANISM for acute vs chronic acidosis in terms of which will INCREASE and which will DECREASE renal EXCRETION of K+?

The Kaplan is a bit confusing on this point...thanks!
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#2
04-13-2007, 03:14 PM
Bump...anyone? thanks!
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#3
04-13-2007, 07:58 PM
acute acidosis slows Na/K pump at parietal cell of distal tubule, causing decrease k secretion
chronic acidosis differs from aldosterone involvement d/t hyperkalemia, aldosterone will up the same Na/K pump again and secret more K. in short, acute decrease K secretion, chronic increase K secretion.
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