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nbme 2 b1 5, 9 - tacrolimus99
#1
A sexually active 20-year-old woman has had fever, chills, malaise, and pain of the
vulva for 2 days. Examination shows a vulvar pustule that has ulcerated and
formed multiple satellite lesions. Nodes are palpated in the inguinal and
femoral areas. A smear of fluid from the lesions establishes the diagnosis.
Which of the following is the most likely causal organism?

A) Chlamydia trachomatis

B) Haemophilus ducreyi

C) Neisseria gonorrhoeae

D) Streptococcus pyogenes (group A)

E) Treponema pallidum

An asymptomatic 57-year-old man with a 3-year history of type 2
diabetes mellitus comes for a routine follow-up visit. Examination shows no
abnormalities. Serum studies show:
Aspartate aminotransferase (AST, GOT) 76 U/L
Alanine aminotransferase (ALT, GPT) 86 U/L
Iron 260 µg/dL Total iron-binding capacity 300 µg/dL (N=250“450)
Ferritin 1200 ng/mL Antinuclear antibody negative
Serologic testing for hepatitis is negative. Which of the following is
the most appropriate next step in management?

A) Corticosteroid therapy

B) Interferon therapy

C) Penicillamine therapy

D) Chronic phlebotomy

E) No therapy indicated
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#2
1) B
2) D
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#3
1)A
2)D
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#4
i believe in clamidia tracomatis, the inguinal lymphadenopathy develops after a couple of weeks, not a the same time
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#5
http://books.google.com.pk/books?id=vNDSEmTBV8kC&pg=PA190&lpg=PA190&dq=satellite+lesions+haemophilus+ducreyi&source=bl&ots=3Z_uniz5PV&sig=xN19YT7G87zxz_o34wy1akA1EX0&hl=en&ei=KwggSpbsA5KHkQX-rMX9BA&sa=X&oi=book_result&ct=result&resnum=1#PPA190,M1


The lesions are satellite lesions along with LN...so it shud be Hemophilus duc...BBBB
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#6
b-painful leison-
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#7
i agree
B
D
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#8
There are many differences and similarities between the conditions chancre (T. pallidum) and chancroid (h. ducreyi)
Similarities
Both originate as pustules at the site of inoculation, and progress to ulcerated lesions
Both lesions are typically 1-2 cm in diameter
Both lesions are caused by sexually transmissible organisms
Both lesions typically appear on the genitals of infected individuals
Both lesions can present at multiple sites and with multiple lesions
Differences
Chancre is a lesion typical of infection with the bacterium that causes syphilis, Treponema pallidum
Chancroid is a lesion typical of infection with the bacterium Haemophilus ducreyi
Chancres are typically painless, whereas chancroid are typically painful
Chancres are typically non-exudative, whereas chancroid typically have a grey or yellow purulent exudate
Chancres have a hard (indurated) edge, whereas chancroid have a soft edge
Chancres heal spontaneously within three to six weeks, even in the absence of treatment
Chancres can occur in the pharynx as well as on the genitals

source: Wikipedia
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#9
BBB
DDD
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