NBME 5/block 2/q 21 ?????????????????? - xanax

[ArchivalUser]

sequence-specific cleavage of proteins plays a role in which of the following processes?
a.activation of G proteins by hormone receptors
b. assembly of microtubules
c. cellular uptake of iron
d. initiation of coagulaton
e. transport of proteins into the nucleus

please explain!!???

[ArchivalUser]

I think the answer is D.

[ArchivalUser]

thanks a lot Mahsa
any body else??

[ArchivalUser]

yep.. d.

xanax, they are asking which physiologic process is one where we have a specific sequence/order in which the involved proteins are cleaved.

The coagulation pathway is an example where one after the other coagulation factors are broken down & activated. This ALWAYS occurs in a SPECIFIC order- XII -- > XI--> IX... and so on till finally prothrombin is cleaved to thrombin which cleaves fibrinogen into fibrin monomers.

Hope I helped just a lil' bit.

[ArchivalUser]

thanks a lot ideigal, I got it

[ArchivalUser]

URW, xanax. :O)