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qqqq? - thrombolyser
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03-04-2010, 01:29 PM
ANTIBIOTICS ARE GIVEN BY TUNNEL CATHETER.............HOW CAN IT EFFFECT GUT FLORA EVEN IF THERE IS LIITLE SECRETION IN INTESTINE FROM BLOOD.................AND THE TIME PERIOD IS VERY NARROW?,,,,,,,,,,,,,,,,,,,,,,,,,,,,,
03-05-2010, 11:40 AM
are you sure is C/ piperacilin interacts with warfarin
03-05-2010, 12:36 PM
antibiotic associated decrease in intestinal flora which led to decrease vit K and inc INR---->most possible explanation
03-05-2010, 12:46 PM
but antibiotics are given by catheter not oral..............thrombo
03-05-2010, 12:48 PM
whaT U R SAYING IS THEY CANT DECREASE INTESTINAL FLORA ----->I DONT THINK SO .THEY CAN DECREASE INTESTINAL FLORA
03-05-2010, 01:04 PM
fine, if the intestinal flora was washed off by the antypseudomonas antibiotics, and there is no vit. K, why the patient doesn't have C. pseudomembranosus colitis
03-05-2010, 01:11 PM
I dont think that there is any hard and fast rule that pt must also develop pseudomembranous colitis----> though I have to search for it and will give u answer in a couple of days.
03-05-2010, 02:43 PM
liana Nearly all antibiotics have been implicated in clostrid difficile associated D, which may range in severity from mild diarrhea to fatal colitis s( this may start during antiibiotherapy or 5 to 10 days, and sometimes more than 2 months after completion of an antimicrobial course of therapy, if this happened you should stop antibiotics( and give antb for CD + fluid).
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