07-10-2013, 02:11 AM
Hyperkalemia is generally defined as the inability of the kidneys to excrete adequate levels of potassium from the body. When digoxin's mechanism kicks-in, then it decreases the use of K+ ions in the sodium-potassium pump by decreasing the NA-K ATPase activity. This reduction leads to a build-up of potassium in the body. Dehydration and various illnesses often are also contributing factors to the change to K+ levels and hyperkalemia. Know more here http://answers.yahoo.com/question/index?...416AAgb2zq and http://forum.internationaldrugmart.com/d...t4382.html