10-28-2011, 12:48 PM
8. A 4-year-old boy has a 2-month history of easy bruisability, petechial hemorrhages, and bleeding gums. He has hepatosplenomegaly and pancytopenia. Examination of
bone marrow shows marrOW infiltration with a homogeneous population of small blast-like cells with large nuclei and scant cytoplasm. These infiltrating cells have the
following immunophenotype: CD22+, CD19+, cytoplasmic Ig~+, cytoplasmic IgK-, cytoplasmic IgA-, surface Ig-, CD3-. The patient most likely has an acute leukemia
originating from which of the following cells?
o A) Immature myelomonocytes
o B) Mature B lymphocytes
o C) Mature monocytes
o D) Mature T lymphocytes
o E) Pre-B lymphocytes
o F) Pre-T lymphocytes
Ans E because it is CD3-and CD 19+ also T-cell should be CD3+
I have a doubt here Goljan on page 235 of rapid review says that T-cell ALL arises from T cells whereas UW says T-cell All arises from Pre T lymphocytes if anybody what is correct pl explain
9. A 32-year-old woman undergoes a laparoscopic cholecystectomy after ultrasonography showed a thickened gallbladder wall and gallstones. The surgeon will be unable to
inspect directly which of the following organs during this procedure?
o A) Ileum
o B) Jejunum
o C) Pancreas
o D) Stomach
o E) Transverse colon
Ans Pancreas being retroperitoneal
18. A 6-hour-old female newbom has a harsh systolic murmur at the left upper stemal border. Findings on physical examination are otherwise unremarkable. Three hours
later, the murmur has a diastolic component Twelve hours later, there is no murmur, and ultrasonography discloses no cardiac abnormalities. Which ofthe following is the
most likely cause of the murmur?
o A) Mitral regurgitation
o B) Patent ductus arteriosus
o C) Persistent truncus arteriosus
o D) Transient tricuspid insufficiency
o E) Ventricular septal defect with right-to-left shunt
Ans is PDA If anyone knows pl explain
40. Assume that any single laboratory test in a three-test battery obtained from healthy volunteers has a 5% chance of falling outside of the "normal" range. Which of the
following is the closest probability that a healthy person will have normal results for all three tests?
o A)5%
o 8)40%
o C)85%
o D)95%
Ans is C why ?/ Pl explain
bone marrow shows marrOW infiltration with a homogeneous population of small blast-like cells with large nuclei and scant cytoplasm. These infiltrating cells have the
following immunophenotype: CD22+, CD19+, cytoplasmic Ig~+, cytoplasmic IgK-, cytoplasmic IgA-, surface Ig-, CD3-. The patient most likely has an acute leukemia
originating from which of the following cells?
o A) Immature myelomonocytes
o B) Mature B lymphocytes
o C) Mature monocytes
o D) Mature T lymphocytes
o E) Pre-B lymphocytes
o F) Pre-T lymphocytes
Ans E because it is CD3-and CD 19+ also T-cell should be CD3+
I have a doubt here Goljan on page 235 of rapid review says that T-cell ALL arises from T cells whereas UW says T-cell All arises from Pre T lymphocytes if anybody what is correct pl explain
9. A 32-year-old woman undergoes a laparoscopic cholecystectomy after ultrasonography showed a thickened gallbladder wall and gallstones. The surgeon will be unable to
inspect directly which of the following organs during this procedure?
o A) Ileum
o B) Jejunum
o C) Pancreas
o D) Stomach
o E) Transverse colon
Ans Pancreas being retroperitoneal
18. A 6-hour-old female newbom has a harsh systolic murmur at the left upper stemal border. Findings on physical examination are otherwise unremarkable. Three hours
later, the murmur has a diastolic component Twelve hours later, there is no murmur, and ultrasonography discloses no cardiac abnormalities. Which ofthe following is the
most likely cause of the murmur?
o A) Mitral regurgitation
o B) Patent ductus arteriosus
o C) Persistent truncus arteriosus
o D) Transient tricuspid insufficiency
o E) Ventricular septal defect with right-to-left shunt
Ans is PDA If anyone knows pl explain
40. Assume that any single laboratory test in a three-test battery obtained from healthy volunteers has a 5% chance of falling outside of the "normal" range. Which of the
following is the closest probability that a healthy person will have normal results for all three tests?
o A)5%
o 8)40%
o C)85%
o D)95%
Ans is C why ?/ Pl explain