|
NonNBME Qn - samideb12
|
02-28-2012, 01:58 PM
Klein-Waardenburg syndrome is a single-gene disorder that includes dystopia canthorum ,impaired hearing,and pigmentary abnormalities .The gene involved is most likely to be a
A.Pseudogne B.Proto-oncogene C.Transgene D.Homeotic gene E.Tumor suppressor gene
02-28-2012, 05:05 PM
gene = PAX 3 ... associated with transcription factor
02-28-2012, 05:11 PM
Yes ,D is the correct answer
Klein -Waardenburg syndrome: ...........defect in the gene called PAX/Homeobox gene ...........the gene codes homeodomain protein ...........homeodomain proteins are transcriptional activators
02-28-2012, 05:28 PM
thankss samideb!! homeobox genes usually encode for phenotypic or anatomic structures.... like organs and etc....
02-28-2012, 05:33 PM
...>Homeodomain proteins are regulatory proteins which are important in controlling embryonic gene expression.These regulatory proteins are encoded by genes called homeobox(HOX) or homeotic genes.
....>Mutations in HOX or PAX genes may produce development errors ;K-W syndrome is one such develomental disorder resulting from a mutation in PA gene |
| « Next Oldest | Next Newest » |
