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Pharm...**4,5,6 - maryam2009
#1
4.All of the following statements about OKT3 (Muromonab-CD3) are true EXCEPT:

A. It blocks cytotoxic T-lymphocyte killer function.
B. It can cause chills and fever.
C. Its major clinical advantage is that it does not cause hypersensitivity reactions.
D. It is used to prevent acute rejection, especially in renal transplants.

.......................

5. Which one of the following statements about the clinical uses of immunosuppressive antibodies is most appropriate?

A. They can be used to inhibit platelet function in a patient undergoing coronary angioplasty.
B. They can be used alone and in combination with other immunosuppressants to suppress rejection of renal transplants.
C. They can be used to suppress immune responses in an Rh-negative mother to prevent hemolytic disease in an Rh-positive fetus in present and future pregnancies.
D. All of the above statements are correct.

....................

6. Which one of the following adverse effects is least likely to be produced by Cyclosporine (Sandimmune)?

A. Neurotoxicity
B. Bone marrow suppression
C. Nephrotoxicity
D. Hepatotoxicity






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#2
4 c
5 d

6 d
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#3
4.c. 5. B. 6.d
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#4
4 c
5 b
6 d
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#5
Correct answers :

4.C
5.D
6.B

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#6
i don't think i understand #5..can you please explain

thanks
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