immuno Q - fadd

[ArchivalUser]

An 18-year-old man is evaluated for possible immunodeficiency disease because of a life-long history of chronic lung infections, recurrent otitis media, and multiple episodes of bacterial meningitis. While total IgG is normal, the patient is found to have a selective deficiency of IgG2. An associated deficiency of which of the following other substances may produce anaphylaxis when blood products are given to such individuals?

A. C3


B. C4


C. IgA


D. IgE


E. IgM

[ArchivalUser]

c.

[ArchivalUser]

right.A potentially clinically important point is that some patients with IgG2 deficiency also have IgA deficiency and may develop anaphylaxis if given IgA-containing blood products.