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A 39-year-old male with aortic insufficiency and a history of no drug allergies is given an intravenous dose of antibiotic as a prophylaxis preceding the insertion of a valve prosthesis. As the antibiotic is being infused, the patient becomes flushed over most of his body.
What antibiotic was given?
A. Vancomycin
B. Gentamicin
C. Erythromycin
D. Penicillin G
E. Tetracycline
What is the mechanism?
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DDD Penicillin G?..vasovagal response ( vasodilation) its too early to cause any type of hypersensitivity at first exposure...pls answer..
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A??
vancomycin -- causes flushing... (Red man Syndrome)
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Vancomycin is right......how does it do that?
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vancomycin causes release of histamine...histamine syndrome ....but how does it cause histamine release ? if not by mast cell degranulation?...
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Other agents that can cause a similar reaction include OPIOIDS, DEXTRAN, and PROTAMINE.
