>??????????????????????????????????? - zen786

[ArchivalUser]

Failure of a Na+/K+ ATPase pump .... will that lead to cellular edema or not ?

[ArchivalUser]

zen u are cheating in my question pal

[ArchivalUser]

of course....it is the earliest step in Hypoxic cell injury, when ATP depletion causes Na/K ATPase pump dysfunction, Na accumulates in the cell, leading to cell swelling.

[ArchivalUser]

no no im not cardio .... im reading this in pathoma right now as we speak .... so i just wanted to confirm something sorry ....



im trying to figure out the correlation of ATP*** itself with edema.... so decrease ATP --> decrease Na/K ---> shouldn't lead to edema...

[ArchivalUser]

any hypoxic injury to a cell will lead to cellualr swelling

[ArchivalUser]

NVM yes wikidr you are right... decrease ATP ==> increase sodium intracellular ==> edema [cellular swelling]

[ArchivalUser]

Na/K ATP ase pump needs ATP in order to function properly, as its name says. if you do not hv ATP, then-----> dec. Na/K atpase activity ------> Na stays inside the cell/ accumulates --------> cellular swelling

[ArchivalUser]

yup thank you herniation and wikidr godbless you guys!!

[ArchivalUser]

ofcourse lead to edema and cell lysis..........