03-15-2006, 01:46 PM
I. white square (1)+ dark circle (2 - deceased) to produce II (2) and II (3)
II. white square(1) + dark circle (2- deceased); dark quare (3 - deceased)+ white circle (4)
Note: II (1) and II(2 - deceased) are a couple to produce III(1 to 3)
II (3) and II (4 - deceased) are a couple to produce III (4 and 5)
III. 1 and 3 are white square, 2 is dark square
4 is dark quare, 5 is white circle
pedigree number (a)
type of neoplasm (b)
age of onset (years) ©
a, b, c
I-2, carcinoma of breast (right), 28
I-2 '''' (left), 36
II-2 carcinoma of breast, 51
II-3 myxofibrosarcoma, 48
III-2 medulloblastoma, 5
III-4 rhabdomyosarcoma, 8
This pedigree shows:
1. variable expressivity
2. multifactorial inheritance
3. anticipation
4. genetic heterogeneity
5. incomplete penetrance
II. white square(1) + dark circle (2- deceased); dark quare (3 - deceased)+ white circle (4)
Note: II (1) and II(2 - deceased) are a couple to produce III(1 to 3)
II (3) and II (4 - deceased) are a couple to produce III (4 and 5)
III. 1 and 3 are white square, 2 is dark square
4 is dark quare, 5 is white circle
pedigree number (a)
type of neoplasm (b)
age of onset (years) ©
a, b, c
I-2, carcinoma of breast (right), 28
I-2 '''' (left), 36
II-2 carcinoma of breast, 51
II-3 myxofibrosarcoma, 48
III-2 medulloblastoma, 5
III-4 rhabdomyosarcoma, 8
This pedigree shows:
1. variable expressivity
2. multifactorial inheritance
3. anticipation
4. genetic heterogeneity
5. incomplete penetrance