12-14-2016, 12:45 AM
1 yo boy diagnosed as a case of PKU, is homologous for point mutation GT ----> AT in intron 12 of affected gene that causing of skipping of exon12. Which explanation for skipping of Exxon 12 in affected gene;
A) alteration in poly adenylation site
B) deletion of 5' untranslated region
C) expansion of trinucleotide repeat
D) gene duplication
E) non homologous recombination
F) non sense mutation
G) RNA splice error
H) X inactivation
A) alteration in poly adenylation site
B) deletion of 5' untranslated region
C) expansion of trinucleotide repeat
D) gene duplication
E) non homologous recombination
F) non sense mutation
G) RNA splice error
H) X inactivation